Introduction. The sign of the hyperdense middle cerebral artery (MCA) evaluated by simple tomography allows predicting ischemic cerebrovascular disease (ICD) with occlusion of a large vessel, however, it is common to identify this sign in residents with high hemoglobin levels without symptoms of ICD. Objectives. To evaluate the correlation between the radiodensity of the MCA and the hemoglobin level in patients with and without ICD, residing in a high-altitude city. Methods. Analytical observational study, including people residing in Cusco (located at 3300 masl) who attended the emergency service and underwent a brain tomography, presenting or not ICD symptoms. ACM radiodensity was measured and correlated with the hemoglobin level. Results. 279 patients were included, the average hemoglobin was 15.1 and standard deviation (DE) of 2.5 mg/dL, in the controls a significant correlation was ...

Objective: To determine the normal values of nerve conduction speed (VCN, acronym in Spanish) parameters from people residing in a city localized at highaltitude. Material and methods: Analytical observational study of people without a comorbid history, residing in Cusco, a city located at 3399 meters above sea level. The motor VCN of the median, ulnar, common peroneal, tibial, and the sensory VCN of the median, ulnar, and sural nerves, their latencies and amplitudes, were evaluated. Results: The study included 56 participants, with a median age of 24 (22-26) years. The latencies of the median, ulnar, and anterior tibial nerves were <5 m/s, and of the peroneal nerves were >5 m/s. The amplitudes of the motor nerves were greater than 5mV and the sensory nerves were above 20μV; the motor velocities were greater than 50m/s, and the sensory nerves were greater than 45m/s. Conclusion: F...

Objective: We aimed to determine the correlation between blood viscosity and cerebral blood flow in people acclimated to chronic hypoxia who have high blood viscosity levels. Materials and methods: A Prospective observational study was conducted in asymptomatic young adults living in Cusco (3399 m altitude). All participants were examined at low and high shear rates (75 and 300 s−1) for simulating the dynamic component of blood viscosity. A transcranial Doppler study of the middle cerebral artery was performed to measure systolic, diastolic, and mean flow velocities (FVs), as well as resistance and pulsatility indexes (PIs). Results: One hundred and thirty-one participants were included. Median viscosity levels were 5.01cP (interquartile range [IQR]: 4.45–5.73cP) at 300 s−1 and 6.16 cP (IQR: 5.58-7.20 cP) at 75 s−1, mean FV was 57 cm/s (IQR: 50–65 cm/s), and the PI was 0.91 (0....

The use of Magnetic Resonance Imaging (MRI) in the diagnosis and follow-up of patients with Multiple Sclerosis (MS) has optimized the care of the affected patients. Several international working groups have tried to clarify and standardize the global use of MRI but, on many occasions, data are extrapolated from other regions, do not contemplate local realities or are difficult to implement. Objective: To reach a consensus on aspects related to the use of MRI in the diagnosis and follow-up of patients with MS in Peru. Material and Methods: A group of Peruvian experts (neurologists and radiologists) worked on the elaboration of the consensus using a remote survey round methodology. Results: The recommendations, established on the basis of published evidence and on the experts’ criteria, focused on the role of both, the conventional MRI techniques and the measurement of brain atrophy in M...