Objective: Determine the antibacterial activity in vitro of five concentrations (6.25, 12.5, 25, 50 and 75 mg / mL) of the alcoholic extract of Caesalpinia spinosa “tara” (EACS) on Porphyromonas gingivalis. Materials and method: The study is experimental, prospective, comparative in vitro and kind, was carried out in the Laboratory of Microbiology, Faculty of Dentistry, San Marcos. Diffusion method was used in plate solutions to confront the alcoholic extract of Caesalpinia spinosa and compared with the positive control chlorhexidine 0.12% and Alcohol 96 º negative control. Results: It was found that the concen-tration of the alcoholic extract of Caesalpinia spinosa has antibacterial effect on Porphyromonas gingivalis, although the increased concentration bears no proportion to the increased diameter of the inhibition zone. Statistical analysis using the Kruskal-Wallis test found no...

Objective: Determine the antibacterial activity in vitro of five concentrations (6.25, 12.5, 25, 50 and 75 mg / mL) of the alcoholic extract of Caesalpinia spinosa “tara” (EACS) on Porphyromonas gingivalis. Materials and method: The study is experimental, prospective, comparative in vitro and kind, was carried out in the Laboratory of Microbiology, Faculty of Dentistry, San Marcos. Diffusion method was used in plate solutions to confront the alcoholic extract of Caesalpinia spinosa and compared with the positive control chlorhexidine 0.12% and Alcohol 96 º negative control. Results: It was found that the concen-tration of the alcoholic extract of Caesalpinia spinosa has antibacterial effect on Porphyromonas gingivalis, although the increased concentration bears no proportion to the increased diameter of the inhibition zone. Statistical analysis using the Kruskal-Wallis test found no...

La periodontitis es una enfermedad de etiología infecciosa que presenta como síntomas el sangrado e inflamación de encías, movilidad dentaria, recesiones gingivales, en las que diversas enfermedades sistémicas favorecen su progresión. Uno de estos agentes más importantes es Porphyromonas gingivalis, especie bacteriana anaeróbica estricta, Gram negativo. A su vez, el uso de antibióticos sistémicos está indicado sólo en ciertos tipos de periodontitis, y no siempre el tratamiento es exitoso. Hoy en día, tanto en medicina general como odontológica, se está investigando nuevas alternativas de tratamientos antibacterianos, dado el continuo aumento de la resistencia bacteriana a los antibióticos convencionales y por las reacciones adversas que estos producen en algunos pacientes. El objetivo principal de este trabajo de investigación es determinar la actividad antibacteriana de...