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artículo
In this paper, the concept of iconography will be analyzed as well as its evolution up to the Hispanic Roman mosaic will be discussed. The discussion of the concept will be divided into three main parts. First, the paper will examine the history of the Roman Invasion of Hispania. Second, the concept of time in Rome will be investigated. Finally, the concept of iconography in time and the evolution of mosaic in Hispania will be discussed.
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artículo
Publicado 2023
Enlace
Enlace
Background/Objectives: Retinoblastoma is a common childhood intraocular malignancy, the bilateral form of which most commonly results from a de novo germline pathogenic variant in the RB1 gene. Both advanced maternal age and decreasing birth order are known to increase the risk of de novo germline pathogenic variants, while the influence of national wealth is understudied. This cohort study aimed to retrospectively observe whether these factors influence the ratio of bilateral retinoblastoma cases compared to unilateral retinoblastoma, thereby inferring an influence on the development of de novo germline pathogenic variants in RB1. Subjects/Methods: Data from 688 patients from 11 centres in 10 countries were analysed using a series of statistical methods. Results: No associations were found between advanced maternal age, birth order or GDP per capita and the ratio of bilateral to unilate...
