Introduction: In our country, organ donation has one of the lowest rates worldwide, many factors intervene so that this index can be increased, since there is a high demand for patients who require altruistic attitude both for potential donors and for their families. Objective: to determine the factors associated with an unfavorable attitude towards organ donation in students of the medical faculty of the Catholic University of Santo Toribio de Mogrovejo in 2015. Material and methods: cross-sectional analytical observational study executed in 377 students of the USAT faculty of medicine, to whom a validated data collection instrument was applied to measure the unfavorable attitude towards organ donation, with a 0.77 reliability according to Crombach's alpha and 0.5 validity according to the KMO test Results: Only 138 students (36.6%) said they agreed with organ donation and had a favorab...