Introduction: Tractional-regmatogen combined retinal detachment occurs when traction from an adjacent area of fibrovascular proliferation causes retinal rupture. Clinical case: A 56-year-old male patient was admitted with decreased visual acuity in OD, associated with myodesopsias, metamorphopsias and photopsias. The evaluation found a visual acuity of perception of hand movement at 10 cm in OD; anterior segment biomicroscopy with slit lamp showed an opacity of crystalline C2 P2 and an intraocular pressure of 10 mmHg. Optical funduscopy found an optic nerve with nasal neovascularization, decreased macular brightness, with zones of fibrovascular proliferation around the 4 vascular arcades, Detachment of the traction and regmatogen retina with 1 peripheral tear between hours 11 and 12. The ultrasound showed an ocular globe with preserved contours, with traction zones, undulating membrane c...

The neuromyelitis optica (NMO) or Devic's disease, previously defined by the occurrence of optical neuritis (NO) and transverse myelitis (MT), is currently considered as a spectrum of autoimmune, inflammatory and demyelinating disorders of the CNS. Clinical case: Patient with 2-week clinical history, characterized by abrupt decrease in visual acuity in both eyes, not associated with pain, concomitantly presents decreased sensitivity in the abdominal region and decreased muscle strength in both lower limbs, which make walking impossible. Results: The discovery of the AQP4 autoantibody (anti-AQP4) and its association with NMO, as well as differences in clinical presentation, laboratory, neuroimaging, response to treatment and prognosis, have allowed differentiating this pathology from multiple sclerosis (MS). Conclusion: The prognosis of patients with NMO...