We report 16 cases of Pemphigus foliaceus occurred at Ucayali, department of Peru. Most of them came from Coronel Portillo, Ucayali’s province (94%), and half of them from Campo Verde district. Eighty per cent belonged to rural areas, 56% were females and 7 children were affected (43%). All patients had generalized skin involvement without mucous membranes compromise. Nikolsky sign was present in 50%. In all cases skin biopsy showed subcorneal acantholysis and only 40% presented pemphigus positive immunofluorescence.

The donovanosis is a sexually transmitted disease wich is onlu diagnosed through biopsy and smears. Out of 2259 biopsies made by Dermatology Service from "Dos de Mayo National Hospital" in Lima-Peru since 1991 to 1994, 35 samples were positives to Leishman staining and HE. 83% (29) corresponded to make and 17% (6) to female, 60% patients ranged between 21 to 30 years old (10). This disease is localized in penis (34%)(12) and perianal (34%)(12) sites. It is important to underline the place of different injuries compared with those of other studies. A finding of injury in vulvus of puerpera is reported.