1
tesis de maestría
Publicado 2018
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Objetivo general: Evaluar la utilidad de los marcadores de inflamación para establecer actividad de enfermedad en pacientes con AR usuarios de terapia anti-TNF en el Hospital Nacional Edgardo Rebagliati Martins. La artritis reumatoide (AR) es una enfermedad autoinmune de etiología desconocida, cuya prevalencia a nivel mundial fluctúa entre 0.5 – 1%, mientras que en América latina fluctúa entre 0.2 – 2.8% y la prevalencia reportada en el Perú es del 0.5%. Se han descrito ciertas ventajas del uso de la terapia biológica, sobre los fármacos modificadores de enfermedad convencionales, como son: efectividad, inicio de acción más rápido, buen control de síntomas y disminución significativa de la progresión radiológica de la enfermedad, con el objetivo de controlar la actividad de la enfermedad, evitar el daño articular y/o progresión de la enfermedad. No obstante, los efec...
2
artículo
Publicado 2021
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Background: This article summarizes the clinical practice guideline (CPG) for the initial pharmacological treatment of lupus nephritis in the Social Security of Peru (EsSalud). Objective: To provide evidence-based clinical recommendations for initial pharmacological treatment of non-refractory adults with class I to V lupus nephritis in EsSalud. Material and Methods: A guideline development group (GDG) was formed, which included specialist physicians and methodologists, who formulated clinical questions. Systematic searches were conducted for systematic reviews and - when deemed relevant - primary studies in PubMed during 2021. Evidence was selected to answer each of the clinical questions posed. The certainty of evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology. In periodic working meetings, the GEG used the GRADE meth...
3
artículo
Publicado 2021
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Background: This article summarizes the clinical practice guideline (CPG) for the initial pharmacological treatment of lupus nephritis in the Social Security of Peru (EsSalud). Objective: To provide evidence-based clinical recommendations for initial pharmacological treatment of non-refractory adults with class I to V lupus nephritis in EsSalud. Material and Methods: A guideline development group (GDG) was formed, which included specialist physicians and methodologists, who formulated clinical questions. Systematic searches were conducted for systematic reviews and - when deemed relevant - primary studies in PubMed during 2021. Evidence was selected to answer each of the clinical questions posed. The certainty of evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology. In periodic working meetings, the GEG used the GRADE meth...
