The aim of this study was to determine the effectiveness of a combination of albendazole and rafoxanide against Fasciola hepatica in cattle from the northern region of Lambayeque fattened in an intensive fattening centre in Lima, Peru. Twenty-one naturally infected bulls treated with a combination of albendazole (9 mg/kg) and rafoxanide (10 mg/kg) (Ranide Forte®, TQC, Peru) were used. The effectiveness of the drug was determined using the faecal egg count reduction test (FECRT) with faecal samples collected on days 14 and 30 of dosing. The number of eggs per gram of faeces (epg) was determined with the FLUKEFINDER® method. The bootstrapping method in the R program was used to generate the 95% confidence intervals. The efficacy of the compound was 94% (90:98 95% CI) on day 14 and 100% on day 30. It is shown that rafoxanide in combination with albendazole is a good therapeutic option aga...

Objective: The study assessed the anthelmintic activity of Artemisia absinthium ethanolic extract for controlling gastrointestinal nematodes in goats, both in vitro using infective larvae and in vivo in naturally infected goats under free-grazing conditions in the region of Ayacucho, Peru. Materials and Methods: For the in vitro assay, a larval motility inhibition test was performed on Trichostrongylus spp. infective larvae from goats using three different dilutions: 150, 175, and 200 mg/ml of the plant extract. In vivo efficacy was evaluated through the fecal egg count reduction test (FECRT), which was applied to 15 naturally infected Creole goats in one community. Animals were randomly assigned to 3 experimental groups and treated orally with 600 mg/kg of the plant extract. Fecal samples were collected directly from the rectum on days 0 (pre-treatment) and 7 and 15 post-treatment for e...