Aim: To identify the factors associated with the academic use of social networks in medical students from 40 faculties in Latin America. Methods: Analytical, cross-sectional analysis of secondary data in medical students from 40 Latin American cities. A self-administered questionnaire was used to evaluate the academic use of social networks and their association with socio-educational characteristics and training in scientific databases. Mixed effects multilevel generalized linear models (MEGLM) were used to estimate prevalence ratios (PR). Results: Of 11587 participants, 57.7% used social networks academically. The level of advanced English increased 1.33 times the prevalence of academic use of social networks (PR: 1.33, 95% CI: 1.24-1.43, p <0.001) while belonging to more than one academic-scientific extracurricular group decreased 34% said prevalence (PR: 0.66, 95% CI: 0.54-0.81, p <0...