Introduction: The EndoFLIP (for its acronym in English: endoluminal functional luminal probe) is a system that measures in real time the compliance index of the gastroesophageal junction and secondary esophageal peristalsis, based on the principle of impedance planimetry. Although this technology is relatively new and its diagnostic usefulness is still being evaluated, its use in clinical practice is increasingly recognized, fundamentally in those patients where there is no conclusive manometric diagnosis of esophageal motor pathology, mainly esophagogastric junction outflow obstruction and achalasia. Objective: The aim of the present study is to describe the experience with EndoFLIP at the San Ignacio University Hospital in Bogotá, Colombia. Material and methods: Descriptive observational case series study, which included patients over 18 years of age who had undergone EndoFLIP at the ...

Introduction: Advanced age is associated with a greater prevalence of oesophageal motor disorders due to increased lower oesophageal sphincter (LES) pressure and decreased peristaltic vigour. Secondary peristalsis is particularly affected by age, which may be related to increased oesophageal dysmotility in older adults. Objectives: To describe the most common oesophageal disorders in older adults undergoing high-resolution oesophageal manometry (HREM) according to the Chicago Classification V4.0. Materials and methods: An observational, descriptive, retrospective, cross-sectional study was conducted at San Ignacio University Hospital. Patients over 65 years of age who underwent HREM for various reasons between 2020 and 2025 were included. Results: Total number of patients included, age and age range. A total of 177 patients aged 65 years or older, with an age range of 68- 76 years, were ...

An adequate approach to refractory gastroesophageal reflux disease (rGERD) for achieving therapeutic success. From the precise definition of rGERD to the characterization of its phenotypes, it will pave the way for the customization of therapy for each patient. In this narrative literature review, the aim is to provide an synthesis of the utility of various diagnostic tools and explore the wide options, both medical and invasive, available for this condition.

Se presenta el caso clínico de un paciente de 67 años, con antecedentes de diabetes mellitus, fibrilación auricular e insuficiencia renal crónica, quien desarrolló cuadro de cetoacidosis diabética y sepsis severa, presentando posteriormente una esofagitis necrotizante aguda, y desarrollo luego de estenosis esofágica que requirió tratamiento con prótesis esofágica metálica autoexpandible con buen resultado clínico.

Introduction: Treatment of functional disorders of the anorectal unit should focus on the underlying cause. Biofeedback therapy is a functional retraining of the pelvic floor that has proven useful in the treatment of constipation associated with dyssynergia and in the management of fecal incontinence. This study describes the first experiences with this form of biofeedback therapy in Colombia. Objective: Describe our experience with biofeedback therapy in the gastrointestinal neurophysiology unit. Materials and methods: This historical cohort included patients with an indication for biofeedback therapy for constipation or fecal incontinence in the gastrointestinal neurophysiology unit during the data collection period. The response to therapy is described by comparing manometric findings before and after 10 biofeedback sessions. Results: 21 patients were included (71.4% women, the avera...

Introduction: Attempts have been made to identify the genetic factors related to susceptibility to inflammatory bowel disease (IBD), and the current conclusions are in favor of a complex pathology model, without a clear hereditary pattern. Objective: To perform phenotypic and genotypic characterization of patients with IBD in Colombian population and to describe its possible association with predisposition. Materials and methods: case series, 16 patients with IBD according to clinical and pathological criteria, onset of gastrointestinal symptoms after 18 years of age. All had pre-test genetic counseling and family trees of at least three generations were made. Also, genotyping, using a multigene panel that included genes related to IBD and some autoimmune disorders. Finally, a genomic analysis of variants was performed. Results: 9 women and 7 men, with mean age of diagnosis of IBD of 35 ...