In this work we document and analyze the hydrological annual cycles characterized by a rapid transition between low and high flows in the Amazonas River (Peruvian Amazon) and we show how these events, which may impact vulnerable riverside residents, are related to regional climate variability. Our analysis is based on comprehensive discharge, rainfall and average suspended sediment data sets. Particular attention is paid to the 2010–11 hydrological year, when an unprecedented abrupt transition from the extreme September 2010 drought (8300 m3s−1) to one of the four highest discharges in April 2011 (49 500 m3s−1) was recorded at Tamshiyacu (Amazonas River). This unusual transition is also observed in average suspended sediments. Years with a rapid increase in discharge are characterized by negative sea surface temperature anomalies in the central equatorial Pacific during austral sum...