The scientific work of Professor Alberto Hurtado begins in 1925, being a resident at Boston City Hospital, where he works alongside Francis Peabody, showing sincere devotion to clinical research, which determines the appreciation of his peers and teachers, who invite you to stay with them in the famous Harvard University. Completed his medical training, he returned to Peru and began researching local issues; his doctoral thesis at the University of San Marcos is on the basal metabolism of the Peruvian Indian, that extends past work studying the effect of hypoxic environment on it.

The authors have studied several blochemical parameters in maternal and cord blood from 18 normal deliveries ocurred in Cerro de Pasco, at an altitude of 14000 ft.; as control 16 cases attended at the Maternity Hospital in Lima (445 ft.9 were studied. Newborn weights were similar: 3205 ± 343 g in C. P. and 3086 ± 495 g in Lima; Apgar score was also similar 8.4 and 8.2  respectively. In cord blood mean values in C. P. were: Hematocril 52.5 % ± 6.5 %; pottassium 6.0 ± 0.9, sodium 146 ± 9.3, chloride 110 ± 7.7 m.Eq ./L creatinine 1.14 ± 0 .3, glycemia 67 ± 19 and urea 32.2 ± 12.9 mg.%. Same determinations in Lima were: Hematocrit 48.8 % ± 4.5, similar to  C. P. (p > 0.05]; pottassium 5.0 ± 0.4, sodium 136 ± 2.2 and chloride 103 ± 2.6 m.Eq ./L; the electrolite valves were lower in Lima with p values of > 0.006, < 0.02 and < 0.001 respectively. Creatinine was 0.84 ± 0.3 mg.% l...

The author has studied four cases of masculinizing ovarian tumor; the age of the patients was between 25-35 years; all of them presented amenorrhea, acne, hirsutism and deepening of the voice, hypertrophy of the clitoris was present in two of the cases. The hormonal determinations revealed a normal excretion of the 17-Ketosteroids in three of them, and a slight increase in the remmanent; the urinary testosterone was increased in all the cases, reaching normal male levels in three of them. The author remarks the value of plasma and urinary testosterone determinations in the study of the virilizing ovarian tumors.

The authors have studied a 23 year old female in whom an ovarian tumor developed during her 3rd pregnancy. The tumor was of the adrenal rest type and virilized both the mother and fetus, that was a pseudohermaphrodite girl; the virilization that occured in the mother receded three months after delivery, and the urinary excretion of Testosterone and 17-Ketosteroids were in the normal range at this point; however, an increase of the 17-Ks occured with the injection of HCG; the authors postulate that the tumor was hormone-dependent, and that the secreted androgens were able to cross the placenta and in this way to virilize the fetus.

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Se conmemora este año el centenario del inicio de la infausta guerra que destrozó al país. Numerosos son los homenajes realizados y también los proyectados y en ellos se evoca el heroísmo y sacrificio de los soldados, marinos y civiles de hace 100 años; sin embargo, escasos han sido hasta ahora los tributados a los médicos peruanos que participaron en la guerra y pagaron con su vida o con sangre su devocación a la patria. 

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Se conmemora este año el centenario del inicio de la infausta guerra que destrozó al país. Numerosos son los homenajes realizados y también los proyectados y en ellos se evoca el heroísmo y sacrificio de los soldados, marinos y civiles de hace 100 años; sin embargo, escasos han sido hasta ahora los tributados a los médicos peruanos que participaron en la guerra y pagaron con su vida o con sangre su devocación a la patria. 

The authors have studied several blochemical parameters in maternal and cord blood from 18 normal deliveries ocurred in Cerro de Pasco, at an altitude of 14000 ft.; as control 16 cases attended at the Maternity Hospital in Lima (445 ft.9 were studied. Newborn weights were similar: 3205 ± 343 g in C. P. and 3086 ± 495 g in Lima; Apgar score was also similar 8.4 and 8.2  respectively. In cord blood mean values in C. P. were: Hematocril 52.5 % ± 6.5 %; pottassium 6.0 ± 0.9, sodium 146 ± 9.3, chloride 110 ± 7.7 m.Eq ./L creatinine 1.14 ± 0 .3, glycemia 67 ± 19 and urea 32.2 ± 12.9 mg.%. Same determinations in Lima were: Hematocrit 48.8 % ± 4.5, similar to  C. P. (p > 0.05]; pottassium 5.0 ± 0.4, sodium 136 ± 2.2 and chloride 103 ± 2.6 m.Eq ./L; the electrolite valves were lower in Lima with p values of > 0.006, < 0.02 and < 0.001 respectively. Creatinine was 0.84 Â...

The author has studied four cases of masculinizing ovarian tumor; the age of the patients was between 25-35 years; all of them presented amenorrhea, acne, hirsutism and deepening of the voice, hypertrophy of the clitoris was present in two of the cases. The hormonal determinations revealed a normal excretion of the 17-Ketosteroids in three of them, and a slight increase in the remmanent; the urinary testosterone was increased in all the cases, reaching normal male levels in three of them. The author remarks the value of plasma and urinary testosterone determinations in the study of the virilizing ovarian tumors.

The authors have studied a 23 year old female in whom an ovarian tumor developed during her 3rd pregnancy. The tumor was of the adrenal rest type and virilized both the mother and fetus, that was a pseudohermaphrodite girl; the virilization that occured in the mother receded three months after delivery, and the urinary excretion of Testosterone and 17-Ketosteroids were in the normal range at this point; however, an increase of the 17-Ks occured with the injection of HCG; the authors postulate that the tumor was hormone-dependent, and that the secreted androgens were able to cross the placenta and in this way to virilize the fetus.

Un grupo de 636 pacientes con el Síndrome de ovario poliquístico diagnosticadas ecográficamente fueron divididas en dos categorías: 1. Ovario poliquístico primario 324 pacientes que no estuvieron asociadas a patología concomitante. 2. Ovario poliquístico secundario 312 pacientes que coexistían con alguna endocrinopatía que se menciona a continuación: * Hiperprolactinamia 248, Síndrome de Cushin 3, Hiperplasia Adrenal congénita 11, Hiperplasia Adrenal de inicio tardío 29, Hipertiroidismo 5, Hipotiroidismo 9, Tumor Ovárico productor de Andrógenos 3, Síndrome de Turner 2, Acantosis Nigricans 2.

In a series of 2,344 patients with polycystic ovarian syndrome diagnosed by ultrasound, plasma prolactin was determined and was found in PCOS prevalence of 15% Hyperprolactinaemia. In a group of 855 patients with hyperprolactinemia polycystic ovary syndrome was valued by ultrasound, finding polycystic ovary syndrome in 42% of patients with hyperprolactinemia.

In a series of 2,344 patients with polycystic ovarian syndrome diagnosed by ultrasound, plasma prolactin was determined and was found in PCOS prevalence of 15% Hyperprolactinaemia. In a group of 855 patients with hyperprolactinemia polycystic ovary syndrome was valued by ultrasound, finding polycystic ovary syndrome in 42% of patients with hyperprolactinemia.

We have evaluated the age of menarche and menopause in the Andean High Altitude. The study was done in III women age ranged from 38 to 62 years old, 49 were from high land living at 4340 m altitude and 62 women from sea level. In women from High Altitude the age of menarche was 14,6 ± 0,2, the age of menopause was 45,3 ± 0,7 and the reproductive live was 30,7 ± 0,9. In women from sea level the age of menarche was 12,6 ± 0,2, the age of menopause was 48,2 ± 0,7 and the reproductive live was 35,4 ± 0,9. These results indicated that in High Altitude the age of menarche occurred 2 years later, the age of menopause was 2,9 years earlier and the reproductive live was 4,8 years shorter than women living at sea level. The pregnancy rate at High Altitude was 7,3 ± 0,5 and at sea level was 2,8 ± 0,4 indicating that the High Altitude does not interfere with the normal reproduction.