Introduction: Complex Regional Pain Syndrome (CRPS) is a pathological entity that carries a high burden of disease and reduces disability-free life expectancy and quality of life. Previously, the research patterns and general characteristics of the scientific production on CRPS have not been evaluated or analyzed. Methods: Cross-sectional bibliometric study that used Scopus as the data source. Results: 3081 documents were selected, published between 1969 and 2024. 69% (n=2126) of the articles corresponded to original articles, followed by 13.2% (n=406); it was observed an international collaboration accounted for 11.49% and an annual scientific growth accounted for 7.63%. The most frequently used terms in CRPS research are causalgia, rehabilitation, allodynia, treatment, and inflammation. Reflex sympathetic dystrophy, causalgia, and spinal cord stimulation are the most popular topics to ...