Objective: To determine immunomodulatory and antitumor effect of the extract of Brassica oleracea L. var. Botrytis "Cauliflower" on immune cells in Mus musculus var. Swiss isogenic with experimental cancer. Biological material: Cauliflower collected Simbal-Trujillo, 35-45 g mice. Method: Induction cancer Benzopyrene, Control Group (CG no treatment), treated: GPa (Quercetin), GP1 (ESPC: D=10mg/Kg/pc); GP2 (ESPC: D=20mg/Kg/pc). It was determined: antibody titer, total count (CTL), differential leukocyte (CDL), body weight for 0, 30, 60 and 90 days; number, size, and evaluation of tumors. Results: The extract has secondary metabolites: steroids, saponins, tannins and flavonoids glycosylated quercitin-3-diglucoside-7-diglucoside and kaempferol-3-diglucoside-7-glucoside. GPa, GP1 and GP2 elevated antibody titer compared to GC (P<0.05). Presents difference CTL, percentage neutrophils, lymphocy...

Objective: To identify and characterize phytoconstituents flavonoids in the inflorescence of Brassica oleracea L. var. Botrytis "Cauliflower" by High performance liquid chromatography and Mass spectrometry. Biological material: Cauliflower collected in Simbal-Trujillo. Method: Qualitative identification of phytoconstituents present in the inflorescence by separation with increasing polarity solvents (ether, ethanol and water) by high performance liquid chromatography (HPLC) and mass spectra (MS / MS), characterization was performed on the products of flavonoids obtained after acid and alkaline hydrolysis. Results: The cauliflower inflorescences presented secondary metabolites as glucosinolates, steroids, saponins, tannins and flavonoids. In the analysis of HPLC-MS / MS was obtained retention time (Rt) of glycosylated flavonoids, identified as acylated derivatives ( R- CO-): Quercetin - 3...