With the purpose to assess the prophylactic effectiveness of Ketotifen in the prevention of the development of wheezing episodes in non-asthmatic children clasified in a high-risk category according to a previousley prepared scale, two groups of 21 children, both similar with respect to age, sex and risk rating, were studied. The children of one group received ketotifen and those of the other group did not, both groups being followed during a 12-month period to estimate the development of wheeziness during that time.  The enviromental factors at home, such as the presence of smokers, pets, carpeted floors, and the number of siblings under 10 years of age, were similar in both groups.  A high correlation between the risk rating and the number of episodes of wheeziness in the group not treated with ketotifeno was encountered, thus confirming the value of the scale used.  In ...

The survey was carried out In two stages. In the first, 84 children divided lnto two equal groups regarding age and sex were surveyed; 42 with bronchial asthma and 42 as a control group. An estimate of the frequency of respiratory processes and individual ato pies during their first three years oflife and the antecedents concerning asthma and ato pies of the parents was made. The asthmalic group presented a statistically greater frequency of rhinopharyngitis and bronchltis, as well as asthma and atopies in the parents. Using these variables, two risk scales were prepared for the subseq uent development of asthma, in accordance with what occurred d uring the fist year or the first three years as a whole. Both scales proved mathematically valid when applied to the groups under survey. In the second stage, 122 children were surveyed who had never presented episodes of wheeziness. They were ...

With the purpose to assess the prophylactic effectiveness of Ketotifen in the prevention of the development of wheezing episodes in non-asthmatic children clasified in a high-risk category according to a previousley prepared scale, two groups of 21 children, both similar with respect to age, sex and risk rating, were studied. The children of one group received ketotifen and those of the other group did not, both groups being followed during a 12-month period to estimate the development of wheeziness during that time.  The enviromental factors at home, such as the presence of smokers, pets, carpeted floors, and the number of siblings under 10 years of age, were similar in both groups.  A high correlation between the risk rating and the number of episodes of wheeziness in the group not treated with ketotifeno was encountered, thus confirming the value of the scale used.  In ...

The survey was carried out In two stages. In the first, 84 children divided lnto two equal groups regarding age and sex were surveyed; 42 with bronchial asthma and 42 as a control group. An estimate of the frequency of respiratory processes and individual ato pies during their first three years oflife and the antecedents concerning asthma and ato pies of the parents was made. The asthmalic group presented a statistically greater frequency of rhinopharyngitis and bronchltis, as well as asthma and atopies in the parents. Using these variables, two risk scales were prepared for the subseq uent development of asthma, in accordance with what occurred d uring the fist year or the first three years as a whole. Both scales proved mathematically valid when applied to the groups under survey. In the second stage, 122 children were surveyed who had never presented episodes of wheeziness. They were ...

Beckwith en 1963 y más tarde Wiedemann en 1964, describieron independientemente un nuevo síndrome cuyas características principales consisten en: macroglosia, onfalocele, gigantismo, visceromegalia hiperplásica y tendencia a la hipoglicemia neonatal. Posteriormente, otros autores han hecho contribuciones importantes para el esclarecimiento de esta entidad describiendo otras numerosas características clínicas y anátomo-patológicas (tabla l). Hasta la fecha se han descrito alrededor de 56 casos de este síndrome. 

Beckwith en 1963 y más tarde Wiedemann en 1964, describieron independientemente un nuevo síndrome cuyas características principales consisten en: macroglosia, onfalocele, gigantismo, visceromegalia hiperplásica y tendencia a la hipoglicemia neonatal. Posteriormente, otros autores han hecho contribuciones importantes para el esclarecimiento de esta entidad describiendo otras numerosas características clínicas y anátomo-patológicas (tabla l). Hasta la fecha se han descrito alrededor de 56 casos de este síndrome.