At present, numerous methodologies have been developed to obtain the maximum use of fish proteins, to satisfy human nutritional demand, this use has been made both from whole fish and from its residues or by-products (liver, head, skin, gonads, skeleton, and viscera) which represent up to 60% of the whole fish. Whole fish and by-products can potentially be used as sources of essential amino acids, collagen, gelatin, polyunsaturated lipids, and enzymes. Using enzymatic technology, protein hydrolysates have been obtained with ample potential for their application as ingredients in the development and production of fortified foods, due to their functional properties (antihypertensive, antioxidant, antimicrobial and immunomodulatory), which can reduce the risk of cancer, aging, diabetes, and cardiovascular diseases. In addition, these hydrolysates have important techno-functional properties ...