En el ámbito de la construcción de viviendas multifamiliares en Lima Metropolitana, muchas empresas constructoras medianas continúan utilizando informes de control de calidad en formato físico durante distintas fases de sus proyectos, lo que conlleva problemas de pérdida de datos, incompatibilidad de formatos y errores humanos. Esta práctica genera ambigüedades al compartir información y dificulta la integridad de los proyectos. Esta tesis se enfoca en proponer una solución a este desafío mediante la implementación de la metodología BIM (Building Information Modeling, por sus siglas en inglés). Se presenta una Guía de Implementación basada en BIM para mejorar la gestión de la información en el área de calidad durante las etapas de estructuras y acabados en proyectos de viviendas multifamiliares. La propuesta tiene como objetivo principal optimizar la generación de info...

Intracytoplasmic sperm injection (ICSI) is an in vitro fertilization technique in which a sperm is injected through a micropipette to achieve fertilization. This technique, widely used in assisted reproduction, causes a moderate deformation of the oocyte membrane, which becomes harmful in some cases. The Piezo-ICSI technique minimizes this deformation because the Piezo device generates submicron vibration in the ICSI micropipette that crosses the zona pellucida without generating any resistance. There is no prior evidence of a pregnancy obtained through this technique in Latin America. Therefore, we present this report as the first case of a 16-week clinical pregnancy with present heartbeat from an embryo fertilized using the Piezo-ICSI technique.

Objectives:To identify contraction (CT) patterns in human blastocysts using a Time-Lapse incubator and to correlate them with their ploidy status by PGT-A analysis, the time they took to reach blastocyst state, implantation rate and clinical pregnancy rate. Design: Retrospective cohort study. Interventions: From October 2016 through May 2018, 270 patients were evaluated, 912 embryos were cultivated in the Time-Lapse (Embryoscope™, Vitrolife) incubator; 778 of them were tested for aneuploidy using an NGS platform in a reference laboratory. Vitrification was performed according to the result of embryo development and awaiting the NGS result, followed by devitrification and transfer of a single embryo. Blastocyst contractions (CT) were determined using the EmbryoViewer (EmbryoViewer™ drawing tools) in order to obtain area, percentage of contraction and the various types of contractions,...

Objectives: To determine if the use of the KIDScore 5 algorithm (known implantation data) can help select between euploid embryos in order to improve pregnancy and implantation rates in patients undergoing assisted reproductive procedures. Methods: Retrospective cohort study in a fertility clinic, from October 2016 to December 2018, of 1 049 embryos from 328 patients. All the embryos were cultured in the Time-Lapse, Embryoscope® incubator (Vitrolife®, Canada) for 5-6 days. Of these, 896 embryos (85.4%) were biopsied and analyzed by NGS, and assessed with the predictive KIDScore 5 algorithm (Vitrolife®, Canada). The 153 remaining embryos (14.6%) were assessed with the predictive KIDScore 5 algorithm only. 256 single euploid embryos were transferred in couples undergoing IVF treatments at the Inmater clinic’s laboratory of assisted reproduction in Lima – Peru. Results: The implantat...