Objective: To describe the semiology of Psychogenic Non-Epileptic Seizures (PNES) in patients diagnosed by video-electroencephalogram (VEEG) in a national epilepsy center. Methods: An observational, descriptive, and retrospective study of patients older than 14 years, admitted for telemetry monitoring at the Epilepsy Unit of the National Hospital Edgardo Rebagliati Martins in Lima, Peru, between January 1st, 2017, and December 31, 2022. A definitive diagnosis of PNES was reached through VEEG. Results: Twenty of 26 studied patients were female and 6 male. Most patients experienced loss of posture with falls (92%), gradual onset (88%), some degree of altered consciousness or responsiveness during the event (73%). The most prevalent motor signs included asynchronous movements of the trunk and/or extremities (73%), fluctuation in motor activity (73%), global or limb tremors (54%), and forced...

This research has been supported by the JPI-Belmont project PACMEDY (via grant ANR-15-JCLI-0003-01 for MC, PB, ME, OM, TC, and BT). MC, JC, DO, RSG, AP, and PR acknowledge funding from Concejo Nacional de Ciencia y Tecnologia de Peru (grant n° 007-2017-FONDECYT , grant n° 034-2019-FONDECYT-BM ). SPH acknowledges funding from the ERC-funded project GC2.0 Global Change 2.0: Unlocking the past for a clearer future, grant number 694481 and from the JPI-Belmont project PACMEDY (via NERC ). The distribution and analyses of the transient Holocene simulations with the IPSL model benefit from the Institut Pierre Simon Laplace Climate Modeling Centre Infrastructure supported by ANR “Investissements d'avenir” program ANR-11-IDEX-0004-17-EURE-0006 .