Because of climate change, much attention is drawn to the Amazon River basin, whose hydrology has already been strongly affected by extreme events during the past 20 years. Hydrological annual extreme variations (i.e. low/high flows) associated with precipitation (and evapotranspiration) changes are investigated over the Amazon River sub-basins using the land surface model ORCHIDEE and a multimodel approach. Climate change scenarios from up to eight AR4 Global Climate Models based on three emission scenarios were used to build future hydrological projections in the region, for two periods of the 21st century. For the middle of the century under the SRESA1B scenario, no change is found in high flow on the main stem of the Amazon River (Obidos station), but a systematic discharge decrease is simulated during the recession period, leading to a 10% low-flow decrease. Contrasting discharge va...