In the original publication [1], the funder “MEAE AMBASS FRANCE AU PEROU FSPI—S-AC23007, Filière Santé Maladie Rare «TeteCou-CRANIOST»” must be modified by “This research received no external funding” due to the fact that, since it is a computationaldeveloped article, the use of funds was not necessary.

Cranial neural crest cells are implicated in multiple transcriptional events at the different stages of differentiation during development. The alteration of some transcription factors expressed during neural crest development, like PAX7, could be implicated in the etiology of face malformation in murine models. Epigenetic regulation has been shown to be an important mechanistic actor in the control of timing and the level of gene expression at different stages of neural crest development. During this work, we investigated the interconnection between epigenetics and transcription factors across a diversity of human development cranial neural crest cells. Across a diversity of neural cells from human developing cranial tissues, in accordance with their proliferation stage, an alternative balance of regulation between transcription factors and epigenetic factors was identified.