Determina el efecto antiinflamatorio de los extractos acuosos liofilizados de las hojas de los tres eocotipos de Bixa orellana (Achiote) a dosis de 100 y 200 mg/kg administrada por via oral, mediante el modelo de granuloma inducido por pellets de algodón en ratas albinas (Rattus norvegicus)

Introduction. Antioxidants have shown chemopreventive potential in degenerative, inflammatory, autoimmune, oncology and respiratory distress associated pathologies. Objective. To assess the phytochemical and antioxidant properties in vitro by DPPH and ABTS method. Design. Observational analytical. Location. Laboratory of Experimental Pharmacology, Faculty of Medicine, Universidad Nacional Mayor de San Marcos, Lima, Peru. Biological/Chemical Material. Aloe vera leaves, Plukenetia volubilis seeds, Caiophora carduifolia leaves-stalks, Cecropia membranacea leaves. Interventions. Observation and analysis of the antioxidant capacity by DPPH-method mean effective concentration (EC50) of the extracts and trolox equivalent antioxidant capacity by the ABTS method. Main outcome measures. Phytochemical preliminary march, antioxidant percent uptake inhibition by DPPH radical, determination of equival...