Objective: To determine the positivity and patterns of positive results of rapid antibody tests against SARS-CoV-2 in patients attending to an Emergency Service. Material and methods: Retrospective evaluation of the rapid antibody tests against SARS-CoV-2 applied during the month of June 2020 in the Emergency Service of the Hospital EsSalud G.Almenara, Lima, Peru. Results: We included 1805 tests performed on the same number of patients. In 864 (48%) of the tests were positive, in the following order: combined IgM-IgG pattern in 635 (73%), IgM in 134 (16%) and finally IgG in 95 (11%). Conclusions: The positivity of the rapid antibody tests against SARS-CoV-2 was 48%, and the combined pattern of IgM-IgG was the most frequent in three quarters of the confirmed cases.

Orihuela y Pérez, dos estudiantes de medicina, abordan en una Carta al Editor un potencial efecto clínico adverso a nivel renal de la interacción entre fumarato de disoproxilo de tenofovir (tenofovir DF, TDF) y sofosbuvir/velpatasvir (SOF/VEL)

El estudio se fundamenta en que en nuestro país no se ha hecho una evaluación de la educación médica como un todo, un sistema que considere la duración del proceso, la fragmentación y la desarticulación del mismo. Por tanto, el objetivo consistió en analizar el modelo de formación de médicos internistas en el país, mostrar que es inadecuado y construir un nuevo modelo. El método de estudio fue el de descripción y análisis con una propuesta de racionalización e integración del modelo actual. Se estudió el pregrado y el posgrado en un solo proceso. Asimismo, los ámbitos profesional y académico. También se realizó un trabajo de gabinete y se aplicó una encuesta estructurada y amplia a 194 médicos internistas quienes conformaron una muestra de conveniencia.

Objective: To determine the positivity and patterns of positive results of rapid antibody tests against SARS-CoV-2 in patients attending to an Emergency Service. Material and methods: Retrospective evaluation of the rapid antibody tests against SARS-CoV-2 applied during the month of June 2020 in the Emergency Service of the Hospital EsSalud G.Almenara, Lima, Peru. Results: We included 1805 tests performed on the same number of patients. In 864 (48%) of the tests were positive, in the following order: combined IgM-IgG pattern in 635 (73%), IgM in 134 (16%) and finally IgG in 95 (11%). Conclusions: The positivity of the rapid antibody tests against SARS-CoV-2 was 48%, and the combined pattern of IgM-IgG was the most frequent in three quarters of the confirmed cases.

 Objective: To identify laboratory results associated with the risk of death in patients hospitalized for COVID-19. Material and methods: retrospective cohort study of patients admitted for COVID-19 at the Hospital Nacional EsSalud Guillermo Almenara Irigoyen in Lima, between March 21 and May 12, 2020. The laboratory tests included in the study were those of hospital admission. A Cox analysis was done to determine factors associated with death. Results: a total of 433 patients were included: 253 cases (58%) with positive RT-PCR and 180 cases (42%) with reactive rapid antibody test. And, 55% (240/433) and 59% (256/433) had leukocytosis and relative lymphopenia (≤10%), respectively. 56% (49/87) had D-dimer greater than two mg/L. However, higher than normal values were presented in 39% (152/393) for urea and 19% (77/397) for creatinine, as well as 73% (228/313) for aspartate aminotra...

Creemos que será de interés para los lectores de la revista de la SPMI presentar una reciente serie de casos de sífilis ocular  asociada a pacientes con el virus de inmunodeficiencia adquirida humano (VIH) como alerta clínica en el marco de la pandemia de la COVID-19.

En este documento se plasma la evaluación de la eficacia y seguridad del uso del producto farmacéutico vacuna recombinante nonavalente contra el virus del papiloma humano en pacientes de ambos sexos, entre 9 a 26 años, seropositivos para el virus de inmunodeficiencia humana; cuyos resultados sustentaron la no aprobación del uso de esta tecnología sanitaria en EsSalud.