Objective: To evaluate if prolonged exposure to digital screens in medicine students at a private university would increase the probability of suffering from Computer Vision Syndrome (CVS). Materials and methods: A cross-sectional study in human medicine students from Universidad CientIfica del Sur was performed, using non-probabilistic convenience sampling. The CVS was virtually assessed using the SVI-Q questionnaire, considering demographic characteristics, screen exposure, preventive measures, and ocular diseases. Results: Most students were women (64.08%), with 20-years median age. Nearly sixty percent (59.2%) used glasses (mainly with frames), 55.8% had myopia, and 48.5% had astigmatism. The analysis revealed that screen exposure for four hours or more during virtual classes was related to having CVS (p<0.001). Other related factors were the prolonged use of electronic devices an...