1
artículo
Publicado 2024
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Introducción : El cáncer testicular es la neoplasia maligna sólida más común en pacientes jóvenes entre 15 y 44 años , con tendencia al alza durante la última década. Objetivo : Evaluar los valores del índice Neutrófilo-Linfocito (INL) en la supervivencia de pacientes diagnosticados con cáncer testicular. Materiales y Métodos : Metanálisis de modelo de efectos aleatorios evaluando la supervivencia general y la supervivencia libre de progresión , cumpliendo 6 estudios con los criterios de inclusión. Resultados : Se incluyeron 6 estudios , de los cuales se obtuvo una población total de 1315 . Se evaluó los niveles altos del INL , los cuales se asociaron a una menor supervivencia general (HR: 1.75;IC del 95%: 1,04 - 2,92, I2 : 65%). Conclusión : Se encontró asociación entre niveles elevados de INL y menor supervivencia general , a pesar de esto se determinó que este re...
2
artículo
Publicado 2024
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Background: The neutrophil-to-lymphocyte ratio (NLR) is a biomarker in inflammatory processes associated with multiple unfavorable outcomes in various diseases. This study aims to evaluate the association between NLR values and survival outcomes in patients diagnosed with testicular cancer. Methods: A systematic search was conducted in 6 electronic databases to retrieve studies evaluating NLR in patients with testicular cancer. The outcomes sought were overall survival (OS) and progression-free survival (PFS), and the effect measures were hazard ratio (HR) with a 95% confidence interval (CI). A random effects model was used for the meta-analysis. The risk of bias included in the studies was assessed according to the Newcastle–Ottawa Scale criteria. Egger test and Trim-and-fill method were used to test the publication bias among articles. Results: Six cohort studies (n= 1315) were evalu...
3
artículo
Publicado 2024
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Background: The neutrophil-to-lymphocyte ratio (NLR) is a biomarker in inflammatory processes associated with multiple unfavorable outcomes in various diseases. This study aims to evaluate the association between NLR values and survival outcomes in patients diagnosed with testicular cancer. Methods: A systematic search was conducted in 6 electronic databases to retrieve studies evaluating NLR in patients with testicular cancer. The outcomes sought were overall survival (OS) and progression-free survival (PFS), and the effect measures were hazard ratio (HR) with a 95% confidence interval (CI). A random effects model was used for the meta-analysis. The risk of bias included in the studies was assessed according to the Newcastle–Ottawa Scale criteria. Egger test and Trim-and-fill method were used to test the publication bias among articles. Results: Six cohort studies (n= 1315) were eval...