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The management of ST-segment elevation acute myocardial infarction after reperfusion involves critical decisions for patients with multivessel disease (MVD), acute heart failure, and left ventricular (LV) thrombus. Complete revascularization of non-culprit lesions ≥70% is recommended during the initial intervention or within the first 19 days, particularly in stable patients. Coronary artery bypass grafting is indicated for high-risk anatomies or complex lesions following a successful coronary intervention, where a hybrid strategy combines percutaneous intervention with surgery, with timing adjusted based on whether a stent was implanted. Post-infarction heart failure is common (28-31%) and requires urgent treatment. Continuous monitoring and prompt intervention can reduce complications. In cases of shock or mechanical complications, an intra-aortic balloon pump and inotropic support m...

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