Aim: It has been reported that resin composites may experience alterations in their mechanical properties when they come into contact with glove powder. Therefore, the present study aimed to compare the surface microhardness of 3 bulk-fill resin composites handled with latex and nitrile gloves prior to light curing. Methods: This in vitro experimental study consisted of 90 resin composite specimens with a 6-mm diameter and a 4-mm height divided equally and randomly into 9 groups. Prior to light curing, the resin composites were handled with latex gloves, nitrile gloves, or only a spatula (control). Subsequently, the surface microhardness was measured with an Electronic Vickers Hardness Tester. The Kruskal–Wallis nonparametric H test with Bonferroni correction was used for comparisons. A significance level of 5% (P < .05) was considered. Results: When comparing surface microhardness of ...