La medicina tradicional peruana ha empleado desde tiempos remotos a especies de la familia Gentianaceae, así como al Smallanthus sonchifolius para el tratamiento de Diabetes Mellitus. El objetivo de este trabajo fue comparar el efecto hipoglucemiante de extractos acuosos de Gentianella bicolor, Gentianella nitida, Gentianella chamuchui y Smallanthus sonchifolius en Rattus rattus. Se conformaron 07 grupos de experimentación de 07 animales cada uno; el grupo 01 estuvo conformado por animales sanos y el resto de los grupos por animales con diabetes inducida por administración de Estreptozotocina (60 mg/kg, i.p). Un grupo de ratas diabéticas fue tomado como control positivo, otro grupo recibió 10 mg/Kg de peso de glibenclamida y al resto de los grupos se le administró una dosis diaria de 500 mg/kg de peso de extracto acuoso de Gentianella bicolor, Gentianella nítida, Gentianella chamu...

Gentianella thyrsoidea (Hook.) Fabris is an herbaceous species that grows in localities of the north of Peru, at 3800-4900 m.a.s.l. Despite the wide popular use, no studies have been found to determine its lipid-lowering activity, so this research is aimed to evaluate the hypolipidemic effect of aqueous extract of Gentianella thyrsoidea in Sprague Dawley rats with induced hyperlipidemic. Twenty-four male specimens of Rattus norvegicus Sprague Dawley strain were randomly divided into two experimental groups (EG1 and EG2) and one control group (CG). Every group was induced to hyperlipidemia by administration of 2.5 ml/day of fused tallow trough orogastric way per two weeks. They were given treatment for three weeks: aqueous extract of Gentianella thyrsoidea to experimental groups (250 mg/kg and 500 mg/kg respectively) and saline solution to control g...

Gentianella thyrsoidea (Hook.) Fabris is an herbaceous species that grows in localities of the north of Peru, at 3800-4900 m.a.s.l. Despite the wide popular use, no studies have been found to determine its lipid-lowering activity, so this research is aimed to evaluate the hypolipidemic effect of aqueous extract of Gentianella thyrsoidea in Sprague Dawley rats with induced hyperlipidemic. Twenty-four male specimens of Rattus norvegicus Sprague Dawley strain were randomly divided into two experimental groups (EG1 and EG2) and one control group (CG). Every group was induced to hyperlipidemia by administration of 2.5 ml/day of fused tallow trough orogastric way per two weeks. They were given treatment for three weeks: aqueous extract of Gentianella thyrsoidea to experimental groups (250 mg/kg and 500 mg/kg respectively) and saline solution to control g...

Se determina la actividad inhibidora de proteasas del extracto acuoso de los órganos vegetativos y reproductivos de Ismene amancaes (Ker Gawl.) Herb. (Amaryllidaceae) "amancaes" endémica del Perú. Se hizo un extracto homogenizado de los órganos vegetativos y reproductivos de la planta, utilizando diferentes tampones o buffers de extracción. Después de preparados los extractos vegetales, pasaron por el proceso de liofilización, donde se obtuvieron los diferentes liofilizados, los cuales se resuspendieron en dos tampones distintos. Dichos tampones fueron buffer Tris HCl 100 mM pH 8,0 (números pares) y EDTA +DTT (números impares), resuspendiéndose en la dilución de 1:10, por cada gramo de liofilizado se agregaba 10 ml del tampón. A cada uno de estos extractos acuosos se les realizó el método de clarificación con TCA 2,5 y 5% y se les determinó el porcentaje de concentración...

Se determina la actividad inhibidora de proteasas del extracto acuoso de los órganos vegetativos y reproductivos de Ismene amancaes (Ker Gawl.) Herb. (Amaryllidaceae) "amancaes" endémica del Perú. Se hizo un extracto homogenizado de los órganos vegetativos y reproductivos de la planta, utilizando diferentes tampones o buffers de extracción. Después de preparados los extractos vegetales, pasaron por el proceso de liofilización, donde se obtuvieron los diferentes liofilizados, los cuales se resuspendieron en dos tampones distintos. Dichos tampones fueron buffer Tris HCl 100 mM pH 8,0 (números pares) y EDTA +DTT (números impares), resuspendiéndose en la dilución de 1:10, por cada gramo de liofilizado se agregaba 10 ml del tampón. A cada uno de estos extractos acuosos se les realizó el método de clarificación con TCA 2,5 y 5% y se les determinó el porcentaje de concentración...

Gentianella thyrsoidea (Hook.) Fabris is an herbaceous species that grows in localities of the north of Peru, at 3800-4900 m.a.s.l. Despite the wide popular use, no studies have been found to determine its lipid-lowering activity, so this research is aimed to evaluate the hypolipidemic effect of aqueous extract of Gentianella thyrsoidea in Sprague Dawley rats with induced hyperlipidemic. Twenty-four male specimens of Rattus norvegicus Sprague Dawley strain were randomly divided into two experimental groups (EG1 and EG2) and one control group (CG). Every group was induced to hyperlipidemia by administration of 2.5 ml/day of fused tallow trough orogastric way per two weeks. They were given treatment for three weeks: aqueous extract of Gentianella thyrsoidea to experimental groups (250 mg/kg and 500 mg/kg respectively) and saline solution to control g...

Gentianella thyrsoidea (Hook.) Fabris is an herbaceous species that grows in localities of the north of Peru, at 3800-4900 m.a.s.l. Despite the wide popular use, no studies have been found to determine its lipid-lowering activity, so this research is aimed to evaluate the hypolipidemic effect of aqueous extract of Gentianella thyrsoidea in Sprague Dawley rats with induced hyperlipidemic. Twenty-four male specimens of Rattus norvegicus Sprague Dawley strain were randomly divided into two experimental groups (EG1 and EG2) and one control group (CG). Every group was induced to hyperlipidemia by administration of 2.5 ml/day of fused tallow trough orogastric way per two weeks. They were given treatment for three weeks: aqueous extract of Gentianella thyrsoidea to experimental groups (250 mg/kg and 500 mg/kg respectively) and saline solution to control g...

During the 2015–2016 fruit production season, a papaya bunchy top (PBT) disease was observed in a papaya production farm located at Region de Piura, northern Peru. Affected plants exhibited symptoms of excessive proliferation of auxiliary shoots at the top or near top of the main stem, shortening of internodes, leaf yellowing, and necrosis of leaf veins. The symptom syndrome suggested possible infection by a phytoplasma, and the recent discovery of a phytoplasmal disease in a nearby vineyard also indicated that a phytoplasma reservoir and potential vector(s) were present in the area. Molecular diagnostic assays for phytoplasma detection were therefore employed. Nested polymerase chain reactions and subsequent nucleotide sequence analysis confirmed that phytoplasma infection did occur in the papaya production farm. The phytoplasma strains found to be associated with the PBT disease are ...