OBJETIVE: To identify the main complications associated with the use of hormone replacement therapy. MATERIALS AND METHODS: observational, cross-sectional and retrospective study of 514 healthy postmenopausal women receiving hormone replacement therapy with 0.625 mg conjugated equine estrogen plus 2.5 mg of medroxyprogesterone acetate per day, during the period between January 1998 and December 2002 . RESULTS: The mean age was 57.5 ± 5.75 years (range, 50-76). The body mass index was abnormal in 87.0% (n = 447) of patients, malnutrition and weight and was found in 12.5% (n = 64) and 0.6% (n = 3), respectively. The incidence of complications associated with hormone therapy was 40.1%. The most frequent were hypertriglyceridemia (31.7%), hypercholesterolemia (25.9%), heart disease (6.2%), endometrial hyperplasia (2.4%) and breast (2.4%) cancer, occurring more frequently (63.2%) in patient...

OBJETIVE: To identify the main complications associated with the use of hormone replacement therapy. MATERIALS AND METHODS: observational, cross-sectional and retrospective study of 514 healthy postmenopausal women receiving hormone replacement therapy with 0.625 mg conjugated equine estrogen plus 2.5 mg of medroxyprogesterone acetate per day, during the period between January 1998 and December 2002 . RESULTS: The mean age was 57.5 ± 5.75 years (range, 50-76). The body mass index was abnormal in 87.0% (n = 447) of patients, malnutrition and weight and was found in 12.5% (n = 64) and 0.6% (n = 3), respectively. The incidence of complications associated with hormone therapy was 40.1%. The most frequent were hypertriglyceridemia (31.7%), hypercholesterolemia (25.9%), heart disease (6.2%), endometrial hyperplasia (2.4%) and breast (2.4%) cancer, occurring more frequently (63.2%) in patient...