Objective: To evaluate the influence of high altitude on C-reactive protein (CRP) levels in adults with abdominal visceral adiposity. Materials and methods: A quantitative study with quasi-experimental design, which included twenty-four (24) male medical students from the National University of Trujillo, selected by non-probability convenience sampling and study subject, evaluated at 0 and 4,386 m.a.s.l., and classified according to their degree of abdominal visceral adiposity: normal (G1) and high (G2). Results: The CRP level of G1 in relation to G2 showed no significant difference. Regarding CRP levels, Wilcoxon rank-sum (non-parametric) test was used for G2 and Student´s t-test was used for G1, with significance being shown in both cases. Conclusions: Variations on CRP levels in high altitude compared to sea level in both groups were significant.

Esta investigación tuvo como objetivo determinar el efecto del Lepidium mayenii Walp, “Maca” sobre la nefrotoxicidad inducida por la ifosfamida en Rattus rattus var.  Holtzman.En 28 días los animales de experimentación fueron divididos en 3 grupos de 10 cada uno. Grupo1: Blanco: solución salina 0.9% (0.5 ml) por vía intraperitoneal (VI) más dieta. Grupo2: Problema I: fueron administradas por vía IP con Ifosfamida 1.2 g/Kg/día por 10 días y luego, fueron administrados maca en solución, 5g/día, por 18 días. Grupo 3. Problema II Recibieron dieta y solución maca 5g/día por 18 días, luego fueron administradas (VI) con Ifosfamida 1.2 g/Kg/día por 10 días. Se analizaron muestras pruebas por espectrofotometría método cinético: Úrea, Creatinina, (sérica y urinaria) además de fósforo, y por Electrodo ión Selectivo (EasyLyte): Sodio y Potasio. Se realizaron cortes hist...

Esta investigación tuvo como objetivo determinar el efecto del Lepidium mayenii Walp, “Maca” sobre la nefrotoxicidad inducida por la ifosfamida en Rattus rattus var.  Holtzman.En 28 días los animales de experimentación fueron divididos en 3 grupos de 10 cada uno. Grupo1: Blanco: solución salina 0.9% (0.5 ml) por vía intraperitoneal (VI) más dieta. Grupo2: Problema I: fueron administradas por vía IP con Ifosfamida 1.2 g/Kg/día por 10 días y luego, fueron administrados maca en solución, 5g/día, por 18 días. Grupo 3. Problema II Recibieron dieta y solución maca 5g/día por 18 días, luego fueron administradas (VI) con Ifosfamida 1.2 g/Kg/día por 10 días. Se analizaron muestras pruebas por espectrofotometría método cinético: Úrea, Creatinina, (sérica y urinaria) además de fósforo, y por Electrodo ión Selectivo (EasyLyte): Sodio y Potasio. Se realizaron cortes hist...

Chagas disease, a parasitic infection caused by the protist Trypanosoma cruzi, affects the poorest populations, living in remote, rural areas and urban slums. Although this drug is effective against Chagas disease it presents a number of serious side effects. In residents of high Andean areas with megacolon it can lead to cardiomyopathies. The aim of this study was to investigate whether dietary supplementation with L-glutamine may alleviate some of these symptoms because of its previously observed anti-inflammatory properties. We studied two groups of T. cruzi-infected mice receiving treatment with nifurtimox. One group was fed the standard diet, while the other group’s diet was supplemented with Glutamine. We found that Glutamine supplementation increases body weight (p<0.001), decreases heart-mass-to-body-mass ratio (p<0.001), and decreases the number of amastigotes present in...

Chagas disease, a parasitic infection caused by the protist Trypanosoma cruzi, affects the poorest populations, living in remote, rural areas and urban slums. Although this drug is effective against Chagas disease it presents a number of serious side effects. In residents of high Andean areas with megacolon it can lead to cardiomyopathies. The aim of this study was to investigate whether dietary supplementation with L-glutamine may alleviate some of these symptoms because of its previously observed anti-inflammatory properties. We studied two groups of T. cruzi-infected mice receiving treatment with nifurtimox. One group was fed the standard diet, while the other group’s diet was supplemented with Glutamine. We found that Glutamine supplementation increases body weight (p<0.001), decreases heart-mass-to-body-mass ratio (p<0.001), and decreases the number of amastigotes present in...

Chagas disease, a parasitic infection caused by the protist Trypanosoma cruzi, affects the poorest populations, living in remote, rural areas and urban slums. Although this drug is effective against Chagas disease it presents a number of serious side effects. In residents of high Andean areas with megacolon it can lead to cardiomyopathies. The aim of this study was to investigate whether dietary supplementation with L-glutamine may alleviate some of these symptoms because of its previously observed anti-inflammatory properties. We studied two groups of T. cruzi-infected mice receiving treatment with nifurtimox. One group was fed the standard diet, while the other group’s diet was supplemented with Glutamine. We found that Glutamine supplementation increases body weight (p<0.001), decreases heart-mass-to-body-mass ratio (p<0.001), and decreases the number of amastigotes present in...

Chagas disease, a parasitic infection caused by the protist Trypanosoma cruzi, affects the poorest populations, living in remote, rural areas and urban slums. Although this drug is effective against Chagas disease it presents a number of serious side effects. In residents of high Andean areas with megacolon it can lead to cardiomyopathies. The aim of this study was to investigate whether dietary supplementation with L-glutamine may alleviate some of these symptoms because of its previously observed anti-inflammatory properties. We studied two groups of T. cruzi-infected mice receiving treatment with nifurtimox. One group was fed the standard diet, while the other group’s diet was supplemented with Glutamine. We found that Glutamine supplementation increases body weight (p<0.001), decreases heart-mass-to-body-mass ratio (p<0.001), and decreases the number of amastigotes present in...