The present study analyzes the characterization of adhesion properties in intermediate layers of asphalt pavement, a critical factor influencing road durability and performance. The research is based on a systematic review of scientific literature, highlighting different methodologies for evaluating interlayer bonding, experimental tests, and international standards such as AASHTO, ASTM, and MTC regulations. A comparative analysis was conducted between samples obtained from the “Improvement of the Santa Maria - Santa Teresa - Hydroelectric Machu Picchu Bridge Road” project and laboratory simulations using the LOTTMAN test. The results demonstrate that the amount of tack coat significantly affects interlayer adhesion. Experimental tests confirmed that a tack coat application rate of 0.4 l/m² provides optimal indirect tensile strength (TSR) values, improving mechanical bonding between...