Objective: To determine the association between depression and the domains of geriatric assessment. Materials and methods: A cross-sectional analytic study was conducted in five highland communities from Ayacucho, Peru. Trained personnel administered structured questionnaires, including the Geriatric Depression Scale (GDS), Pfeiffer Short Portable Mental Status Questionnaire (SPMSQ), Katz Index of Independence in Activities of Daily Living, and Abbreviated and modified Gijon's social-familial evaluation scale (SFES). Sociodemographic information and blood oxygen saturation were collected from among ≥60 years population members (n = 156). For bivariate analysis, Fisher's exact and chi-square tests were used. Bivariate and multivariate Poisson regression with 95% CI were also administered to explore the association of geriatric depression with sociodemographic information, blood oxygen l...