The aim of our investigation was to determine the extent to which the implementation of the ANDUDE program, based on an interactive approach improves reading comprehension in students in the second grade of the Educational Institution Nr. 81007 "Modelo", Trujillo – 2019. Elaborated with a sample of 46 girls from the second grade “D” in the control group and “C” in the experimental group, conformed of 23 students in each section. Using applied research, the quasi-experimental design and as an instrument, a test called: ACL-2 was used. Reaching the conclusion that the application of the program significantly improved the reading comprehension of the students of the experimental group.