Presenta un caso de Tumor fibroso solitario (TFS) localizado en el mesenterio del intestino delgado, que es una neoplasia extremadamente rara, el cuarto caso de los presentados en PubMed. Se trata de un paciente varón de 82 años, quien acudió al servicio de urgencias del Hospital Nacional Guillermo Almenara Irigoyen de EsSalud, con un tiempo de enfermedad de 10 días, por dolor abdominal tipo cólico, que aumentó de intensidad con el transcurrir de los días, acompañado de náuseas, vómitos, fiebre cuantificada de 40°C y trastorno del sensorio. El paciente refirió un cuadro similar hace 4 meses, asociado a dispepsia y disminución involuntaria de 3 kg de peso. Se realizó una laparotomía exploratoria + resección de tumoración de íleon distal y mesenterio + anastomosis ileo-ileal. El informe anatomopatológico de la macroscopia concluyó hemangiopericitoma de riesgo intermedio...

Although the relationship between paracoccidioidomycosis (PCM) and solid tumors has been described more than 80 years ago, reports of PCM and gastric cancer are rare. PCM can present before or concomitantly with the diagnosis of cancer, and its clinical presentation may rise the suspicion of malignancies or be part of reactivation by immunosuppression. We present the case of a 52-year-old Peruvian man with a signet-ring cell (SRC) gastric adenocarcinoma who after 6 chemotherapy sessions with FLOT (docetaxel, oxaliplatin, leucovorin, 5-fluorouracil) presented rapidly growing lung nodules. The lung biopsy showed yeasts compatible with Paracoccidioides sp., so he received initial treatment with itraconazole and after gastrectomy maintenance therapy with trimethoprim/sulfamethoxazole accompanied by tomographic resolution of lesions.

This work was carried out with partial financial support from Fundaçăo de Amparo à Pesquisa do Estado de Săo Paulo - FAPESP, Brazil (Process number 2014/03085–0 ). To Conselho Nacional de Desenvolvimento Científico e Tecnológico - CNPq, Brazil , for fellowship to C.D. Gonzales-Lorenzo (Process number 162741/2015–4 ). The authors would like to express our thanks to Dr. H. Loro from the National Engineering University (UNI), Peru, for allowing us to use the appropriate equipment for optical absorption measurements. Besides, C.D. Gonzales-Lorenzo kindly acknowledges the partial financial support from Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica (CONCYTEC) - Banco Mundial , through its executing unit FONDECYT , Peru (Process number 037-2019-FONDECYT-BM-INC.INV.). A.F. Zatsepin and A.N. Kiryakov were supported by the Russian Science Foundation (Grant N° 21-12...