This work was carried out with the purpose to isolate and structural chemistry elucidate the flavonoids of the leaf from the Smallanthus sonchifolius and to determine his antioxidant and immunological activity in mice Balb/C. The samples were collected in the department of Ayacucho and were extracted with ethanol 80%, while that fats, waxes, and chlorophyll removed with petroleum ether, the aqueous layer was extracted with ethyl acetate. The flavonoids were isolated from the ethyl acetate extract for thin layer chromatography preparative, using the solvents system BAW (4:1:5) and visualized with ultraviolet light at 366 nm. The flavonoids structure was elucidated by ultraviolet spectroscopic, using the Mabry et al tables. It was determined the bioassays utilizing brine shrimp (Artemia salina) and the acute oral toxicity for the doses limit test in mice. The antioxidant activity was evalu...

This work was carried out with the purpose to isolate and structural chemistry elucidate the flavonoids of the leaf from the Smallanthus sonchifolius and to determine his antioxidant and immunological activity in mice Balb/C. The samples were collected in the department of Ayacucho and were extracted with ethanol 80%, while that fats, waxes, and chlorophyll removed with petroleum ether, the aqueous layer was extracted with ethyl acetate. The flavonoids were isolated from the ethyl acetate extract for thin layer chromatography preparative, using the solvents system BAW (4:1:5) and visualized with ultraviolet light at 366 nm. The flavonoids structure was elucidated by ultraviolet spectroscopic, using the Mabry et al tables. It was determined the bioassays utilizing brine shrimp (Artemia salina) and the acute oral toxicity for the doses limit test in mice. The antioxidant activity was evalu...