A community randomised controlled trial evaluating a home-based environmental intervention package of improved stoves, solar water disinfection and kitchen sinks in rural Peru: Rationale, trial design and baseline findings

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clanata@iin.sld.pe
Detalles Bibliográficos
Autores: Hartinger, S.M., Lanata, Claudio F., Hattendorf, J., Gil, I., Verastegui, H., Ochoa, T., Mäusezahl, D.
Formato: artículo
Fecha de Publicación:2015
Institución:Universidad Peruana de Ciencias Aplicadas
Repositorio:UPC-Institucional
Lenguaje:inglés
OAI Identifier:oai:repositorioacademico.upc.edu.pe:10757/347070
Enlace del recurso:http://hdl.handle.net/10757/347070
Nivel de acceso:acceso abierto
Materia:Community randomised trial
Diarrhoea
Acute lower respiratory infections
Hygiene
Hand-washing
Child health
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dc.title.es_PE.fl_str_mv A community randomised controlled trial evaluating a home-based environmental intervention package of improved stoves, solar water disinfection and kitchen sinks in rural Peru: Rationale, trial design and baseline findings
title A community randomised controlled trial evaluating a home-based environmental intervention package of improved stoves, solar water disinfection and kitchen sinks in rural Peru: Rationale, trial design and baseline findings
spellingShingle A community randomised controlled trial evaluating a home-based environmental intervention package of improved stoves, solar water disinfection and kitchen sinks in rural Peru: Rationale, trial design and baseline findings
Hartinger, S.M.
Community randomised trial
Diarrhoea
Acute lower respiratory infections
Hygiene
Hand-washing
Child health
title_short A community randomised controlled trial evaluating a home-based environmental intervention package of improved stoves, solar water disinfection and kitchen sinks in rural Peru: Rationale, trial design and baseline findings
title_full A community randomised controlled trial evaluating a home-based environmental intervention package of improved stoves, solar water disinfection and kitchen sinks in rural Peru: Rationale, trial design and baseline findings
title_fullStr A community randomised controlled trial evaluating a home-based environmental intervention package of improved stoves, solar water disinfection and kitchen sinks in rural Peru: Rationale, trial design and baseline findings
title_full_unstemmed A community randomised controlled trial evaluating a home-based environmental intervention package of improved stoves, solar water disinfection and kitchen sinks in rural Peru: Rationale, trial design and baseline findings
title_sort A community randomised controlled trial evaluating a home-based environmental intervention package of improved stoves, solar water disinfection and kitchen sinks in rural Peru: Rationale, trial design and baseline findings
author Hartinger, S.M.
author_facet Hartinger, S.M.
Lanata, Claudio F.
Hattendorf, J.
Gil, I.
Verastegui, H.
Ochoa, T.
Mäusezahl, D.
author_role author
author2 Lanata, Claudio F.
Hattendorf, J.
Gil, I.
Verastegui, H.
Ochoa, T.
Mäusezahl, D.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Hartinger, S.M.
Lanata, Claudio F.
Hattendorf, J.
Gil, I.
Verastegui, H.
Ochoa, T.
Mäusezahl, D.
dc.subject.es_PE.fl_str_mv Community randomised trial
Diarrhoea
Acute lower respiratory infections
Hygiene
Hand-washing
Child health
topic Community randomised trial
Diarrhoea
Acute lower respiratory infections
Hygiene
Hand-washing
Child health
description clanata@iin.sld.pe
publishDate 2015
dc.date.accessioned.es_PE.fl_str_mv 2015-03-24T18:04:43Z
dc.date.available.es_PE.fl_str_mv 2015-03-24T18:04:43Z
dc.date.issued.fl_str_mv 2015-03-24
dc.type.es_PE.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.issn.es_PE.fl_str_mv 1551-7144
dc.identifier.doi.es_PE.fl_str_mv 10.1016/j.cct.2011.06.006
dc.identifier.uri.es_PE.fl_str_mv http://hdl.handle.net/10757/347070
dc.identifier.journal.es_PE.fl_str_mv Contemporary Clinical Trials
identifier_str_mv 1551-7144
10.1016/j.cct.2011.06.006
Contemporary Clinical Trials
url http://hdl.handle.net/10757/347070
dc.language.iso.es_PE.fl_str_mv eng
language eng
dc.relation.url.es_PE.fl_str_mv http://www.sciencedirect.com/science/article/pii/S1551714411001510
dc.rights.es_PE.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.es_PE.fl_str_mv application/pdf
dc.publisher.es_PE.fl_str_mv Elsevier B.V.
dc.source.es_PE.fl_str_mv Universidad Peruana de Ciencias Aplicadas (UPC)
Repositorio Académico - UPC
dc.source.none.fl_str_mv reponame:UPC-Institucional
instname:Universidad Peruana de Ciencias Aplicadas
instacron:UPC
instname_str Universidad Peruana de Ciencias Aplicadas
instacron_str UPC
institution UPC
reponame_str UPC-Institucional
collection UPC-Institucional
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spelling Hartinger, S.M.Lanata, Claudio F.Hattendorf, J.Gil, I.Verastegui, H.Ochoa, T.Mäusezahl, D.2015-03-24T18:04:43Z2015-03-24T18:04:43Z2015-03-241551-714410.1016/j.cct.2011.06.006http://hdl.handle.net/10757/347070Contemporary Clinical Trialsclanata@iin.sld.peIntroduction: Pneumonia and diarrhoea are leading causes of death in children. There is a need to develop effective interventions. Objective: We present the design and baseline findings of a community-randomised controlled trial in rural Peru to evaluate the health impact of an Integrated Home-based Intervention Package in children aged 6 to 35 months. Methods: We randomised 51 communities. The intervention was developed through a community-participatory approach prior to the trial. They comprised the construction of improved stoves and kitchen sinks, the promotion of hand washing, and solar drinking water disinfection (SODIS). To reduce the potential impact of non-blinding bias, a psychomotor stimulation intervention was implemented in the control arm. The baseline survey included anthropometric and socio-economic characteristics. In a sub-sample we determined the level of faecal contamination of drinking water, hands and kitchen utensils and the prevalence of diarrhoegenic Escherichia coli in stool specimen. Results: We enrolled 534 children. At baseline all households used open fires and 77% had access to piped water supplies. E. coli was found in drinking water in 68% and 64% of the intervention and control households. Diarrhoegenic E. coli strains were isolated from 45/139 stool samples. The proportion of stunted children was 54%. Conclusions: Randomization resulted in comparable study arms. Recently, several critical reviews raised major concerns on the reliability of open health intervention trials, because of uncertain sustainability and non-blinding bias. In this regard, the presented trial featuring objective outcome measures, a simultaneous intervention in the control communities and a 12- month follow up period will provide valuable evidence.This study received financial support of the UBS Optimus Foundation, through a grant given to the IIN and Swiss TPH. The sponsors had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; or preparation, review, or approval of the manuscript.Revisión por paresapplication/pdfengElsevier B.V.http://www.sciencedirect.com/science/article/pii/S1551714411001510info:eu-repo/semantics/openAccessUniversidad Peruana de Ciencias Aplicadas (UPC)Repositorio Académico - UPCreponame:UPC-Institucionalinstname:Universidad Peruana de Ciencias Aplicadasinstacron:UPCCommunity randomised trialc69a2150-79ee-415c-a92e-014fcac01b94600Diarrhoeae46a89b1-0af8-44b3-9da5-544671ba0e3b600Acute lower respiratory infectionsb949c4e7-adce-4ff2-93e5-db2776a380f0600Hygiene10fca567-4e16-4dc8-8438-5a5e1f498eee600Hand-washingc4ca7bcf-282a-49ad-aa8e-7cedae04c332600Child healthb4d00813-d65f-42d5-8f82-421da7281716600A community randomised controlled trial evaluating a home-based environmental intervention package of improved stoves, solar water disinfection and kitchen sinks in rural Peru: Rationale, trial design and baseline findingsinfo:eu-repo/semantics/article2018-06-15T21:28:39ZIntroduction: Pneumonia and diarrhoea are leading causes of death in children. There is a need to develop effective interventions. Objective: We present the design and baseline findings of a community-randomised controlled trial in rural Peru to evaluate the health impact of an Integrated Home-based Intervention Package in children aged 6 to 35 months. Methods: We randomised 51 communities. The intervention was developed through a community-participatory approach prior to the trial. They comprised the construction of improved stoves and kitchen sinks, the promotion of hand washing, and solar drinking water disinfection (SODIS). To reduce the potential impact of non-blinding bias, a psychomotor stimulation intervention was implemented in the control arm. The baseline survey included anthropometric and socio-economic characteristics. In a sub-sample we determined the level of faecal contamination of drinking water, hands and kitchen utensils and the prevalence of diarrhoegenic Escherichia coli in stool specimen. Results: We enrolled 534 children. At baseline all households used open fires and 77% had access to piped water supplies. E. coli was found in drinking water in 68% and 64% of the intervention and control households. Diarrhoegenic E. coli strains were isolated from 45/139 stool samples. The proportion of stunted children was 54%. Conclusions: Randomization resulted in comparable study arms. Recently, several critical reviews raised major concerns on the reliability of open health intervention trials, because of uncertain sustainability and non-blinding bias. 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A community randomised controlled trial evaluating a home-based environmental intervention package of improved stoves, solar water disinfection and kitchen sinks in rural Peru: Rationale, trial design and baseline findings
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