Reacciones adversas identificadas durante el esquema de tratamiento cis-diamino-dicloro-platino-ii (cddp) en pacientes con cáncer cervical del Instituto Regional de enfermedades neoplásicas - norte, durante el año 2015”

• Autor: Vigo García, Christopher Jim
• Formato: tesis de grado
• Fecha de Publicación: 2016
• Institución: Universidad Nacional de Trujillo
• Repositorio: UNITRU-Tesis
• Lenguaje: español
• OAI Identifier: oai:dspace.unitru.edu.pe:20.500.14414/5854
• Enlace del recurso: https://hdl.handle.net/20.500.14414/5854
• Nivel de acceso: acceso abierto
• Materia: Hoja de seguimiento farmacoterapéutico, Instituto regional de enfermedades neoplásicas – norte, Esquema de tratamiento cddp, Reacción adversa

The aim of this study was to classify adverse reactions during the chemotherapy with CDDP (Cisplatin) in patients with cervical cancer, the present research work is descriptive, cross-sectional and retrospective. Information was collected from the pharmacotherapeutic follow up sheets of patients with cervical cancer from the Regional Institute of Neoplastic Diseases - North (IREN - North) of the Oncology Mixtures Unit; All patients received the Cisplatin treatment regimen for a maximum of 6 cycles during the January-December period of 2015. Adverse reactions were classified by frequency, organ system, and severity according to WHO. The most frequent adverse reaction during treatment was anemia (20%), followed by nausea, vomiting, hepatotoxicity, thrombocytosis and pain (12%). The most affected organ systems were: the hematological system (40%), followed by gastrointestinal (32%), hepatobiliary (12%), neurological (12%) and muscular (4%) disorders. Finally, due to their severity, they were moderate and mild in 64% and 36%, respectively