Factores asociados y proporción de la población con anticuerpos contra Yersinia pestis, provincia de Ascope, La Libertad, 2011

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Plague in a disease of great importance in Public Health and global distribution, a very old disease causing three major pandemics of human plague worldwide with millions of human deaths. A cross-sectional observational study was carried out, in which the associated factors and proportion of the pop...

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Detalles Bibliográficos
Autores: Garcia Vara, Patricia, Zuñiga Castro, Rosa Milagros
Formato: otro
Fecha de Publicación:2019
Institución:Universidad Nacional de Trujillo
Repositorio:UNITRU-Tesis
Lenguaje:español
OAI Identifier:oai:dspace.unitru.edu.pe:20.500.14414/15243
Enlace del recurso:https://hdl.handle.net/20.500.14414/15243
Nivel de acceso:acceso abierto
Materia:Yersinia pestis
Peste humana
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dc.title.es_PE.fl_str_mv Factores asociados y proporción de la población con anticuerpos contra Yersinia pestis, provincia de Ascope, La Libertad, 2011
title Factores asociados y proporción de la población con anticuerpos contra Yersinia pestis, provincia de Ascope, La Libertad, 2011
spellingShingle Factores asociados y proporción de la población con anticuerpos contra Yersinia pestis, provincia de Ascope, La Libertad, 2011
Garcia Vara, Patricia
Yersinia pestis
Peste humana
title_short Factores asociados y proporción de la población con anticuerpos contra Yersinia pestis, provincia de Ascope, La Libertad, 2011
title_full Factores asociados y proporción de la población con anticuerpos contra Yersinia pestis, provincia de Ascope, La Libertad, 2011
title_fullStr Factores asociados y proporción de la población con anticuerpos contra Yersinia pestis, provincia de Ascope, La Libertad, 2011
title_full_unstemmed Factores asociados y proporción de la población con anticuerpos contra Yersinia pestis, provincia de Ascope, La Libertad, 2011
title_sort Factores asociados y proporción de la población con anticuerpos contra Yersinia pestis, provincia de Ascope, La Libertad, 2011
author Garcia Vara, Patricia
author_facet Garcia Vara, Patricia
Zuñiga Castro, Rosa Milagros
author_role author
author2 Zuñiga Castro, Rosa Milagros
author2_role author
dc.contributor.advisor.fl_str_mv Pachas Chavez, Paul Esteben
dc.contributor.author.fl_str_mv Garcia Vara, Patricia
Zuñiga Castro, Rosa Milagros
dc.subject.es_PE.fl_str_mv Yersinia pestis
Peste humana
topic Yersinia pestis
Peste humana
description Plague in a disease of great importance in Public Health and global distribution, a very old disease causing three major pandemics of human plague worldwide with millions of human deaths. A cross-sectional observational study was carried out, in which the associated factors and proportion of the population with antibodies against Yersinia pestis, province of Ascope, department of La Libertad, were determined in 2011. In this study, 144 inhabitants of the province of Ascope of the department of La Libertad, which were interviewed and proceeded with the collection of data and samples required for the study, the samples were tested ELISA IgG to determine the proportion of Yersinia pestis. The average age of the inhabitants was 41 years, with 55.56% from 15 to 44 years old, the sex that predominated was female with 70.83%, the education of the inhabitants with full secondary education followed by primary school complete with 49.31% and 39.58 % respectively. The detection of IgG antibodies against Yersinia pestis by means of the ELISA test was 52.78%, in which no differences were found in the presence of IgG antibodies against Yersinia pestis according to sex, in relation to age. IgG antibodies against Yersinia pestis between the ages of 15 to 44, being statistically significant (p <0.001), with increased risk according to the increase in age. With respect to the risk factors associated with the presence of IgG antibodies against Yersinia pestis, it was observed an association of having one type of floor material (OR = 0.27, p = 0.025), raising cats in their homes (OR = 0.31, p = 0.032) and the presence of rats in their homes (OR = 3.34, p = 0.015). It was determined that the risk factors associated with Yersinia pestis infection by the IgG ELISA test were age and rats. As well as the protective effect factor was the breeding of cats. The present study will broaden the knowledge about this disease caused by Yersinia pestis in Perú.
publishDate 2019
dc.date.accessioned.none.fl_str_mv 12/2/2019 14:33
dc.date.available.none.fl_str_mv 12/2/2019 14:33
dc.date.issued.fl_str_mv 2019
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dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.14414/15243
url https://hdl.handle.net/20.500.14414/15243
dc.language.iso.es_PE.fl_str_mv spa
language spa
dc.relation.ispartofseries.none.fl_str_mv Tesis Segunda Especialidad;TSE-0075, TSE-0076
dc.rights.es_PE.fl_str_mv info:eu-repo/semantics/openAccess
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eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-nd/2.5/pe/
dc.publisher.es_PE.fl_str_mv Universidad Nacional de Trujillo
dc.source.es_PE.fl_str_mv Universidad Nacional de Trujillo
Repositorio institucional - UNITRU
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spelling Pachas Chavez, Paul EstebenGarcia Vara, PatriciaZuñiga Castro, Rosa Milagros12/2/2019 14:3312/2/2019 14:332019https://hdl.handle.net/20.500.14414/15243Plague in a disease of great importance in Public Health and global distribution, a very old disease causing three major pandemics of human plague worldwide with millions of human deaths. A cross-sectional observational study was carried out, in which the associated factors and proportion of the population with antibodies against Yersinia pestis, province of Ascope, department of La Libertad, were determined in 2011. In this study, 144 inhabitants of the province of Ascope of the department of La Libertad, which were interviewed and proceeded with the collection of data and samples required for the study, the samples were tested ELISA IgG to determine the proportion of Yersinia pestis. The average age of the inhabitants was 41 years, with 55.56% from 15 to 44 years old, the sex that predominated was female with 70.83%, the education of the inhabitants with full secondary education followed by primary school complete with 49.31% and 39.58 % respectively. The detection of IgG antibodies against Yersinia pestis by means of the ELISA test was 52.78%, in which no differences were found in the presence of IgG antibodies against Yersinia pestis according to sex, in relation to age. IgG antibodies against Yersinia pestis between the ages of 15 to 44, being statistically significant (p <0.001), with increased risk according to the increase in age. With respect to the risk factors associated with the presence of IgG antibodies against Yersinia pestis, it was observed an association of having one type of floor material (OR = 0.27, p = 0.025), raising cats in their homes (OR = 0.31, p = 0.032) and the presence of rats in their homes (OR = 3.34, p = 0.015). It was determined that the risk factors associated with Yersinia pestis infection by the IgG ELISA test were age and rats. As well as the protective effect factor was the breeding of cats. The present study will broaden the knowledge about this disease caused by Yersinia pestis in Perú.La peste en una enfermedad de mucha importancia en Salud Pública y de distribución mundial, enfermedad muy antigua causante de tres grandes pandemias de peste humana a nivel mundial con millones de muertes humanas. Se realizó un estudio observacional transversal, en el que se determinó los factores asociados y proporción de la población con anticuerpos contra Yersinia pestis, provincia de Ascope, departamento de La Libertad durante el 2011. En este estudio se enroló a 144 habitantes de la provincia de Ascope del departamento de La Libertad, a los que se les entrevisto y se procedió con la recolección de los datos y muestras requeridas para el estudio, a las muestras se les realizó la prueba de ELISA Ig G para determinar la proporción de Yersinia pestis. La edad promedio de los habitantes fue 41 años, con un 55.56% de 15 a 44 años, el sexo que predominó fue femenino con un 70.83%, la educación de los habitantes con estudios de secundaria completa seguida de primaria completa con 49.31% y 39.58% respectivamente. La detección de anticuerpos IgG contra Yersinia pestis mediante la prueba de ELISA fue de un 52.78%, a la que no se encontró diferencias en la presencia de anticuerpos IgG contra Yersinia pestis según el sexo, en relación a la edad, se observó mayor presencia de anticuerpos IgG contra Yersinia pestis entre los años de edad de 15 a 44, siendo estadísticamente significativo (p<0,001), con incremento de riesgo según el aumento de la edad. Con respecto a los factores de riesgo asociados a la presencia de Anticuerpos Ig G contra Yersinia pestis se observó asociación el tener un tipo de material de piso (OR=0.27, p=0,025), el criar gatos en sus viviendas (OR=0.31, p=0,032) y la presencia de ratas en sus viviendas (OR=3.34, p=0,015). Se determinó que los factores de riesgo asociados a la infección por Yersinia pestis mediante la prueba de ELISA IgG, fueron la edad y ratas. Así como el factor efecto protector fue la crianza de gatos. El presente estudio permitirá ampliar el conocimiento acerca de esta enfermedad causada por Yersinia pestis en el Perú.Tesis de segunda especialidadspaUniversidad Nacional de TrujilloTesis Segunda Especialidad;TSE-0075, TSE-0076info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/2.5/pe/Universidad Nacional de TrujilloRepositorio institucional - UNITRUreponame:UNITRU-Tesisinstname:Universidad Nacional de Trujilloinstacron:UNITRUYersinia pestisPeste humanaFactores asociados y proporción de la población con anticuerpos contra Yersinia pestis, provincia de Ascope, La Libertad, 2011info:eu-repo/semantics/otherTítulo de Segunda EspecialidadSegunda EspecialidadEspecialista en EpidemiologíaUniversidad Nacional de Trujillo.Facultad de Ciencias BiólogicasLICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://dspace.unitru.edu.pe/bitstreams/3cd343b3-67d7-400c-8fc1-a5fd05956b08/download8a4605be74aa9ea9d79846c1fba20a33MD52ORIGINALGarcia Vara, Patricia y Zuñiga Castro, Rosa Milagros.pdfGarcia Vara, Patricia y Zuñiga Castro, Rosa Milagros.pdfapplication/pdf1591375https://dspace.unitru.edu.pe/bitstreams/3f9f7e83-b49f-4a4a-b536-92ee70659cc7/downloadce8f398fbb429dc31bf9f28e67e067b0MD5320.500.14414/15243oai:dspace.unitru.edu.pe:20.500.14414/152432024-07-01 19:44:44.507http://creativecommons.org/licenses/by-nc-nd/2.5/pe/info:eu-repo/semantics/openAccessopen.accesshttps://dspace.unitru.edu.peRepositorio Institucional - UNITRUrepositorios@unitru.edu.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