Toxic megacolon. Case report: Megacolon tóxico: a propósito de un caso

• Autores: Sernaque Mechato, Roger, Castillo Arias, Stephanie Tahnne, Ñaupari Jara, Silvana, Mendoza Barreto, Flor Milagros
• Formato: artículo
• Fecha de Publicación: 2024
• Institución: Universidad Ricardo Palma
• Repositorio: Revistas - Universidad Ricardo Palma
• Lenguaje: español; inglés
• OAI Identifier: oai:oai.revistas.urp.edu.pe:article/6468
• Enlace del recurso: http://revistas.urp.edu.pe/index.php/RFMH/article/view/6468
• Nivel de acceso: acceso abierto
• Materia: Megacolon tóxico, colitis ulcerativa, Clostridium difficile, shock; Toxic megacolon, ulcerative colitis, clostridium difficile, shock

Toxic megacolon is a fatal disease, most commonly occurring as a complication of inflammatory bowel disease, infections, and intestinal ischemia. It is characterized by the presence of bloody diarrhea, abdominal distension, signs of systemic toxicity, and segmental colonic dilation is observed in imaging studies. The diagnosis according to Jalan's criteria are: colonic dilation more than 6cm, three of the following: fever, tachycardia, leukocytosis or anemia, and any of the following criteria: hypotension, hypovolemia, electrolyte disorder and altered mental status. This article presents the case of a female patient who was admitted with abdominal pain and chronic diarrhea with an imaging study showing dilation of the entire colonic framework. The corresponding studies were carried out which indicated that she had a toxic megacolon due to colitis. ulcerative, receives medical treatment with favorable evolution, is discharged and readmitted for septic shock, studies are performed and Clostridium difficile infection is identified, antibiotic treatment is started but the evolution is unfavorable, which caused the death of the patient. The present case represents the high mortality of this disease.