Nitrosamine production by Candida albicans and its relationship with lesions of the oral cavity. A literature review

• Autores: Gili, María A., Segovia, Silvia Mariana, Lezcano, Melisa Raquel
• Formato: artículo
• Fecha de Publicación: 2021
• Institución: Universidad Nacional Mayor de San Marcos
• Repositorio: Revistas - Universidad Nacional Mayor de San Marcos
• Lenguaje: español
• OAI Identifier: oai:ojs.csi.unmsm:article/19700
• Enlace del recurso: https://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/19700
• Nivel de acceso: acceso abierto
• Materia: Candida albicans; Oral candidiasis; Nitrosamines; Buccal dysplasia; (source: MeSH NLM); Candidiasis bucal; Nitrosaminas; Displasia bucal; (fuente: DeCS BIREME)

This literature review was carried out to approach the state of knowledge regarding the capacity of Candida Albicans to produce nitrosamines and how these are related to the possible malignancy of lesions in the oral cavity. Oral candidiasis (CO) is a frequent infection of the oral mucosa caused by fungi of the family Candida spp. These fungi are part of the usual oral flora but, due to different local and systemic factors, can produce superficial mycosis. Among the different species, Albicans is the most frequent in the oral cavity. It has a great variety of virulence factors, one of them the nitrosation capacity of nitrates and nitrites present in saliva that lately has been considered related to the malignization of mucosal lesions of the oral cavity and others such as the stomach.