Consequences of gamma radiation to mice skin

• Autores: Chávez Soto, Blanca, Estrada, Lourdes, Hurtado, Jorge, López, Zarela, Mancisidor, Karina, Manco, Roxana, Paredes, José, Pareja, Jesús, Puycan, Liliana, Ramírez, Patricia
• Formato: artículo
• Fecha de Publicación: 2000
• Institución: Universidad Nacional Mayor de San Marcos
• Repositorio: Revistas - Universidad Nacional Mayor de San Marcos
• Lenguaje: español
• OAI Identifier: oai:ojs.csi.unmsm:article/4370
• Enlace del recurso: https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/4370
• Nivel de acceso: acceso abierto
• Materia: Radiation; gamma rays; whole-body irradiation; research; Radiación; rayos gamma; irradiación corporal total; investigación

OBJECTIVE: To determine clinical, biochemical, hematologic and histopathologic effects caused by gamma radiation to mice skin. MATERIAL AND METHODS: Experimental case-control study in 30 albino Balc-10 mice irradiated with fractionated doses, 1.2, 1.8, 3.0, and 3.6 Gy, during 3 sessions with one week interval. RESULTS: Alterations produced with radiation threshold values below 3 Gy were directly related to dose increase, with inverse effect noted above threshold values and remarkable organism response to detrimental action. There was marked reduction in blood cells, mainly lymphocytes. CONCLUSIONS: Gamma irradiation produces various effects that depend on dosage and number of irradiations.