Rabies encephalitis or post-vaccination encephalitis in a pregnant woman with a surviving premature neonate
Descripción del Articulo
Human rabies is a serious infection that requires application of rabies serum and vaccine, which can cause post-vaccination acute demyelinating encephalomyelitis (ADEM). We report a 27-year-old pregnant woman who has been bitten by a dog on her right hand. She didn’t receive rabies serum but she rec...
| Autores: | , , |
|---|---|
| Formato: | artículo |
| Fecha de Publicación: | 2022 |
| Institución: | Universidad Nacional Mayor de San Marcos |
| Repositorio: | Revistas - Universidad Nacional Mayor de San Marcos |
| Lenguaje: | español |
| OAI Identifier: | oai:revistasinvestigacion.unmsm.edu.pe:article/20363 |
| Enlace del recurso: | https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/20363 |
| Nivel de acceso: | acceso abierto |
| Materia: | Virus de la Rabia Vacunas Antirrábicas Encefalitis Embarazo Recién Nacido Prematuro Rabies Virus Rabies Vaccines Encephalitis Pregnancy Infant Premature |
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Rabies encephalitis or post-vaccination encephalitis in a pregnant woman with a surviving premature neonateEncefalitis por rabia o encefalitis post-vacunal en mujer gestante con neonato prematuro sobrevivienteTapia-Pérez, RafaelBarreda-de la Cruz, MiguelAlvarez-Gamero, Julio C.Tapia-Pérez, RafaelBarreda-de la Cruz, MiguelAlvarez-Gamero, Julio C.Virus de la RabiaVacunas AntirrábicasEncefalitisEmbarazoRecién NacidoPrematuroRabies VirusRabies VaccinesEncephalitisPregnancyInfantPrematureHuman rabies is a serious infection that requires application of rabies serum and vaccine, which can cause post-vaccination acute demyelinating encephalomyelitis (ADEM). We report a 27-year-old pregnant woman who has been bitten by a dog on her right hand. She didn’t receive rabies serum but she received 5 vaccinations. With last vaccination she presents hand numbness, malaise, fever, hydrophobia, altered consciousness. A cesarean section was performed and the patient was induced a therapeutic coma. Nape skin biopsy and inoculation in mice were negative, while seroneutralization in mice and detection of anti-rabies antibodies were positive. In umbilical cord, mouse seroneutralization was positive. Magnetic resonance imaging revealed lesions compatible with ADEM. By some criteria, it could be rabies; however, the chart would be more compatible with ADEM.La rabia humana es una infección grave que requiere aplicación de suero antirrábico y vacuna, la cual puede producir encefalomielitis desmielinizante aguda (EDMA) post-vacunal. Se reporta una gestante de 27 años mordida por un perro en mano derecha. No recibió suero antirrábico pero sí 5 vacunas. Con última vacuna presentó adormecimiento de mano, malestar, fiebre, hidrofobia, alteración de conciencia. Se realizó cesárea e indujo al coma terapéutico. La biopsia de piel de nuca e inoculación en ratón fueron negativos mientras que la seroneutralización en ratón y detección de anticuerpos antirrábicos fueron positivos. En cordón umbilical, la seroneutralización en ratón fue positiva. La resonancia magnética evidenció lesiones compatibles con EDMA. Según algunos criterios, podría tratarse de rabia; sin embargo, el cuadro sería más compatible con EDMA.Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana2022-01-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/2036310.15381/anales.v82i4.20363Anales de la Facultad de Medicina; Vol. 82 No. 4 (2021)Anales de la Facultad de Medicina; Vol. 82 Núm. 4 (2021)1609-94191025-5583reponame:Revistas - Universidad Nacional Mayor de San Marcosinstname:Universidad Nacional Mayor de San Marcosinstacron:UNMSMspahttps://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/20363/17671Derechos de autor 2022 Anales de la Facultad de Medicinahttp://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccessoai:revistasinvestigacion.unmsm.edu.pe:article/203632022-02-10T11:44:03Z |
| dc.title.none.fl_str_mv |
Rabies encephalitis or post-vaccination encephalitis in a pregnant woman with a surviving premature neonate Encefalitis por rabia o encefalitis post-vacunal en mujer gestante con neonato prematuro sobreviviente |
| title |
Rabies encephalitis or post-vaccination encephalitis in a pregnant woman with a surviving premature neonate |
| spellingShingle |
Rabies encephalitis or post-vaccination encephalitis in a pregnant woman with a surviving premature neonate Tapia-Pérez, Rafael Virus de la Rabia Vacunas Antirrábicas Encefalitis Embarazo Recién Nacido Prematuro Rabies Virus Rabies Vaccines Encephalitis Pregnancy Infant Premature |
| title_short |
Rabies encephalitis or post-vaccination encephalitis in a pregnant woman with a surviving premature neonate |
| title_full |
Rabies encephalitis or post-vaccination encephalitis in a pregnant woman with a surviving premature neonate |
| title_fullStr |
Rabies encephalitis or post-vaccination encephalitis in a pregnant woman with a surviving premature neonate |
| title_full_unstemmed |
Rabies encephalitis or post-vaccination encephalitis in a pregnant woman with a surviving premature neonate |
| title_sort |
Rabies encephalitis or post-vaccination encephalitis in a pregnant woman with a surviving premature neonate |
| dc.creator.none.fl_str_mv |
Tapia-Pérez, Rafael Barreda-de la Cruz, Miguel Alvarez-Gamero, Julio C. Tapia-Pérez, Rafael Barreda-de la Cruz, Miguel Alvarez-Gamero, Julio C. |
| author |
Tapia-Pérez, Rafael |
| author_facet |
Tapia-Pérez, Rafael Barreda-de la Cruz, Miguel Alvarez-Gamero, Julio C. |
| author_role |
author |
| author2 |
Barreda-de la Cruz, Miguel Alvarez-Gamero, Julio C. |
| author2_role |
author author |
| dc.subject.none.fl_str_mv |
Virus de la Rabia Vacunas Antirrábicas Encefalitis Embarazo Recién Nacido Prematuro Rabies Virus Rabies Vaccines Encephalitis Pregnancy Infant Premature |
| topic |
Virus de la Rabia Vacunas Antirrábicas Encefalitis Embarazo Recién Nacido Prematuro Rabies Virus Rabies Vaccines Encephalitis Pregnancy Infant Premature |
| description |
Human rabies is a serious infection that requires application of rabies serum and vaccine, which can cause post-vaccination acute demyelinating encephalomyelitis (ADEM). We report a 27-year-old pregnant woman who has been bitten by a dog on her right hand. She didn’t receive rabies serum but she received 5 vaccinations. With last vaccination she presents hand numbness, malaise, fever, hydrophobia, altered consciousness. A cesarean section was performed and the patient was induced a therapeutic coma. Nape skin biopsy and inoculation in mice were negative, while seroneutralization in mice and detection of anti-rabies antibodies were positive. In umbilical cord, mouse seroneutralization was positive. Magnetic resonance imaging revealed lesions compatible with ADEM. By some criteria, it could be rabies; however, the chart would be more compatible with ADEM. |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022-01-11 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/20363 10.15381/anales.v82i4.20363 |
| url |
https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/20363 |
| identifier_str_mv |
10.15381/anales.v82i4.20363 |
| dc.language.none.fl_str_mv |
spa |
| language |
spa |
| dc.relation.none.fl_str_mv |
https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/20363/17671 |
| dc.rights.none.fl_str_mv |
Derechos de autor 2022 Anales de la Facultad de Medicina http://creativecommons.org/licenses/by-nc-sa/4.0 info:eu-repo/semantics/openAccess |
| rights_invalid_str_mv |
Derechos de autor 2022 Anales de la Facultad de Medicina http://creativecommons.org/licenses/by-nc-sa/4.0 |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
application/pdf |
| dc.publisher.none.fl_str_mv |
Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana |
| publisher.none.fl_str_mv |
Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana |
| dc.source.none.fl_str_mv |
Anales de la Facultad de Medicina; Vol. 82 No. 4 (2021) Anales de la Facultad de Medicina; Vol. 82 Núm. 4 (2021) 1609-9419 1025-5583 reponame:Revistas - Universidad Nacional Mayor de San Marcos instname:Universidad Nacional Mayor de San Marcos instacron:UNMSM |
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Universidad Nacional Mayor de San Marcos |
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UNMSM |
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UNMSM |
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Revistas - Universidad Nacional Mayor de San Marcos |
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Revistas - Universidad Nacional Mayor de San Marcos |
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1848424382491262976 |
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13.915032 |
Nota importante:
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).
