USING OF FIRST GENERATION OF Hl ANTIHISTAMINES As ALTERNATIVE OF LOCAL ANESTHETIC IN ODONTOLOGIC USE IN ANESTHESIA INFILTRATIVE TECHNICS. EXPERIMENTAL STUDY IN ANIMALS

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The presence of adverse drug reactions with local anesthetics takes us to the search of effective alternatives to this drugs. 60 albino rabbits divided into 6 groups were submifted to infiltrative anesthetic technique in the maxilla with lidocaine, mepivacaine, bupivacaine, chlorpheniramine and dime...

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Autores: Rodríguez Alfaro, Miguel, Burga Sánchez, Jonny, Chumpitaz Cerrate, Victor, Varas Hilario, Roberto, López Bellido, Roger, Chuquihuaccha Granda, Vilma, Zegarra Cuya, Juan
Formato: artículo
Fecha de Publicación:2004
Institución:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Lenguaje:español
OAI Identifier:oai:ojs.csi.unmsm:article/3413
Enlace del recurso:https://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/3413
Nivel de acceso:acceso abierto
Materia:Anestesia local
anestésicos locales
antihistamínicos
umbral doloroso
inflamación
técnica infiltrativa
Local anesthesia
local anestetics
antihistamines
pain tlzreshold
inflamation
infiltrative technique
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spelling USING OF FIRST GENERATION OF Hl ANTIHISTAMINES As ALTERNATIVE OF LOCAL ANESTHETIC IN ODONTOLOGIC USE IN ANESTHESIA INFILTRATIVE TECHNICS. EXPERIMENTAL STUDY IN ANIMALSEMPLEO DE ANTIHISTAMÍNICOS H1 DE PRIMERA GENERACIÓN COMO ALTERNATIVA A LOS ANESTÉSICOS LOCALES DE USO ODONTOLÓGICO EN TÉCNICAS DE ANESTESIA INFILTRATIVA. ESTUDIO EXPERIMENTAL EN ANIMALESRodríguez Alfaro, MiguelBurga Sánchez, JonnyChumpitaz Cerrate, VictorVaras Hilario, RobertoLópez Bellido, RogerChuquihuaccha Granda, VilmaZegarra Cuya, JuanAnestesia localanestésicos localesantihistamínicosumbral dolorosoinflamacióntécnica infiltrativaLocal anesthesialocal anesteticsantihistaminespain tlzresholdinflamationinfiltrative techniqueThe presence of adverse drug reactions with local anesthetics takes us to the search of effective alternatives to this drugs. 60 albino rabbits divided into 6 groups were submifted to infiltrative anesthetic technique in the maxilla with lidocaine, mepivacaine, bupivacaine, chlorpheniramine and dimenhidrinate, in front of sodium chloride 0,9%. The pain threshold belzavior was evaluated with electrical stimulation from Ruhnkorff s bobbin behind the drllg application and comparison between groups was made. The wlzite llsed drugs elevated the pain threshold, with a better response of lidocaine. Both local anesthetics and antihistamine drugs produced an effective local anesthesia, without tissue damage.La producción de reacciones adversas medicamentosas con anestésicos locales nos lleva a la búsqueda de alternativas efectivas a estos fármacos. 60 conejos albinos divididos en 6 grupos fueron sometidos a la técnica de anestesia infiltrativa del maxilar superior, con lidocaína, mepivacaína, bupivacaína, clorfeniramina y dimenhidrinato, frente al control con cloruro de sodio al 0,9 %. Se evaluó el comportamiento del umbral doloroso ante la estimulación eléctrica con carrete de Ruhnkorff tras la administración de las drogas y se hizo la comparación entre grupos. Todas las drogas utilizadas produjeron aumento del umbral del dolor frente al grupo control, siendo la lidocaína la droga que produjo una disminución mayor de la respuesta ante el estímulo eléctrico. Tanto los anestésicos locales como los antihistamínicos produjeron anestesia local efectiva, sin daño tisular marcado.Universidad Nacional Mayor de San Marcos, Facultad de Odontología2004-12-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/341310.15381/os.v8i2.3413Odontología Sanmarquina; Vol. 8 No. 2 (2004); 20-24Odontología Sanmarquina; Vol. 8 Núm. 2 (2004); 20-241609-86171560-9111reponame:Revistas - Universidad Nacional Mayor de San Marcosinstname:Universidad Nacional Mayor de San Marcosinstacron:UNMSMspahttps://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/3413/4716Derechos de autor 2004 Miguel Rodríguez Alfaro, Jonny Burga Sánchez, Victor Chumpitaz Cerrate, Roberto Varas Hilario, Roger López Bellido, Vilma Chuquihuaccha Granda, Juan Zegarra Cuyahttps://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccessoai:ojs.csi.unmsm:article/34132020-03-21T18:09:52Z
dc.title.none.fl_str_mv USING OF FIRST GENERATION OF Hl ANTIHISTAMINES As ALTERNATIVE OF LOCAL ANESTHETIC IN ODONTOLOGIC USE IN ANESTHESIA INFILTRATIVE TECHNICS. EXPERIMENTAL STUDY IN ANIMALS
EMPLEO DE ANTIHISTAMÍNICOS H1 DE PRIMERA GENERACIÓN COMO ALTERNATIVA A LOS ANESTÉSICOS LOCALES DE USO ODONTOLÓGICO EN TÉCNICAS DE ANESTESIA INFILTRATIVA. ESTUDIO EXPERIMENTAL EN ANIMALES
title USING OF FIRST GENERATION OF Hl ANTIHISTAMINES As ALTERNATIVE OF LOCAL ANESTHETIC IN ODONTOLOGIC USE IN ANESTHESIA INFILTRATIVE TECHNICS. EXPERIMENTAL STUDY IN ANIMALS
spellingShingle USING OF FIRST GENERATION OF Hl ANTIHISTAMINES As ALTERNATIVE OF LOCAL ANESTHETIC IN ODONTOLOGIC USE IN ANESTHESIA INFILTRATIVE TECHNICS. EXPERIMENTAL STUDY IN ANIMALS
Rodríguez Alfaro, Miguel
Anestesia local
anestésicos locales
antihistamínicos
umbral doloroso
inflamación
técnica infiltrativa
Local anesthesia
local anestetics
antihistamines
pain tlzreshold
inflamation
infiltrative technique
title_short USING OF FIRST GENERATION OF Hl ANTIHISTAMINES As ALTERNATIVE OF LOCAL ANESTHETIC IN ODONTOLOGIC USE IN ANESTHESIA INFILTRATIVE TECHNICS. EXPERIMENTAL STUDY IN ANIMALS
title_full USING OF FIRST GENERATION OF Hl ANTIHISTAMINES As ALTERNATIVE OF LOCAL ANESTHETIC IN ODONTOLOGIC USE IN ANESTHESIA INFILTRATIVE TECHNICS. EXPERIMENTAL STUDY IN ANIMALS
title_fullStr USING OF FIRST GENERATION OF Hl ANTIHISTAMINES As ALTERNATIVE OF LOCAL ANESTHETIC IN ODONTOLOGIC USE IN ANESTHESIA INFILTRATIVE TECHNICS. EXPERIMENTAL STUDY IN ANIMALS
title_full_unstemmed USING OF FIRST GENERATION OF Hl ANTIHISTAMINES As ALTERNATIVE OF LOCAL ANESTHETIC IN ODONTOLOGIC USE IN ANESTHESIA INFILTRATIVE TECHNICS. EXPERIMENTAL STUDY IN ANIMALS
title_sort USING OF FIRST GENERATION OF Hl ANTIHISTAMINES As ALTERNATIVE OF LOCAL ANESTHETIC IN ODONTOLOGIC USE IN ANESTHESIA INFILTRATIVE TECHNICS. EXPERIMENTAL STUDY IN ANIMALS
dc.creator.none.fl_str_mv Rodríguez Alfaro, Miguel
Burga Sánchez, Jonny
Chumpitaz Cerrate, Victor
Varas Hilario, Roberto
López Bellido, Roger
Chuquihuaccha Granda, Vilma
Zegarra Cuya, Juan
author Rodríguez Alfaro, Miguel
author_facet Rodríguez Alfaro, Miguel
Burga Sánchez, Jonny
Chumpitaz Cerrate, Victor
Varas Hilario, Roberto
López Bellido, Roger
Chuquihuaccha Granda, Vilma
Zegarra Cuya, Juan
author_role author
author2 Burga Sánchez, Jonny
Chumpitaz Cerrate, Victor
Varas Hilario, Roberto
López Bellido, Roger
Chuquihuaccha Granda, Vilma
Zegarra Cuya, Juan
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Anestesia local
anestésicos locales
antihistamínicos
umbral doloroso
inflamación
técnica infiltrativa
Local anesthesia
local anestetics
antihistamines
pain tlzreshold
inflamation
infiltrative technique
topic Anestesia local
anestésicos locales
antihistamínicos
umbral doloroso
inflamación
técnica infiltrativa
Local anesthesia
local anestetics
antihistamines
pain tlzreshold
inflamation
infiltrative technique
description The presence of adverse drug reactions with local anesthetics takes us to the search of effective alternatives to this drugs. 60 albino rabbits divided into 6 groups were submifted to infiltrative anesthetic technique in the maxilla with lidocaine, mepivacaine, bupivacaine, chlorpheniramine and dimenhidrinate, in front of sodium chloride 0,9%. The pain threshold belzavior was evaluated with electrical stimulation from Ruhnkorff s bobbin behind the drllg application and comparison between groups was made. The wlzite llsed drugs elevated the pain threshold, with a better response of lidocaine. Both local anesthetics and antihistamine drugs produced an effective local anesthesia, without tissue damage.
publishDate 2004
dc.date.none.fl_str_mv 2004-12-31
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/3413
10.15381/os.v8i2.3413
url https://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/3413
identifier_str_mv 10.15381/os.v8i2.3413
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/3413/4716
dc.rights.none.fl_str_mv https://creativecommons.org/licenses/by-nc-sa/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Odontología
publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Odontología
dc.source.none.fl_str_mv Odontología Sanmarquina; Vol. 8 No. 2 (2004); 20-24
Odontología Sanmarquina; Vol. 8 Núm. 2 (2004); 20-24
1609-8617
1560-9111
reponame:Revistas - Universidad Nacional Mayor de San Marcos
instname:Universidad Nacional Mayor de San Marcos
instacron:UNMSM
instname_str Universidad Nacional Mayor de San Marcos
instacron_str UNMSM
institution UNMSM
reponame_str Revistas - Universidad Nacional Mayor de San Marcos
collection Revistas - Universidad Nacional Mayor de San Marcos
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1795238208878936064
score 13.860643
USING OF FIRST GENERATION OF Hl ANTIHISTAMINES As ALTERNATIVE OF LOCAL ANESTHETIC IN ODONTOLOGIC USE IN ANESTHESIA INFILTRATIVE TECHNICS. EXPERIMENTAL STUDY IN ANIMALS
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