USING OF FIRST GENERATION OF Hl ANTIHISTAMINES As ALTERNATIVE OF LOCAL ANESTHETIC IN ODONTOLOGIC USE IN ANESTHESIA INFILTRATIVE TECHNICS. EXPERIMENTAL STUDY IN ANIMALS

• Autores: Rodríguez Alfaro, Miguel, Burga Sánchez, Jonny, Chumpitaz Cerrate, Victor, Varas Hilario, Roberto, López Bellido, Roger, Chuquihuaccha Granda, Vilma, Zegarra Cuya, Juan
• Formato: artículo
• Fecha de Publicación: 2004
• Institución: Universidad Nacional Mayor de San Marcos
• Repositorio: Revistas - Universidad Nacional Mayor de San Marcos
• Lenguaje: español
• OAI Identifier: oai:ojs.csi.unmsm:article/3413
• Enlace del recurso: https://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/3413
• Nivel de acceso: acceso abierto
• Materia: Anestesia local; anestésicos locales; antihistamínicos; umbral doloroso; inflamación; técnica infiltrativa; Local anesthesia; local anestetics; antihistamines; pain tlzreshold; inflamation; infiltrative technique

The presence of adverse drug reactions with local anesthetics takes us to the search of effective alternatives to this drugs. 60 albino rabbits divided into 6 groups were submifted to infiltrative anesthetic technique in the maxilla with lidocaine, mepivacaine, bupivacaine, chlorpheniramine and dimenhidrinate, in front of sodium chloride 0,9%. The pain threshold belzavior was evaluated with electrical stimulation from Ruhnkorff s bobbin behind the drllg application and comparison between groups was made. The wlzite llsed drugs elevated the pain threshold, with a better response of lidocaine. Both local anesthetics and antihistamine drugs produced an effective local anesthesia, without tissue damage.