The anorexigenic effect of intra-mesopallium ghrelin is related to high plasma corticosterone levels in broiler chicks during the first week of life

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Ghrelin is peptide secreted primarily in the stomach that acts on the central nervous system to regulate energy metabolism and responses to stress. In chicken, it decreases feed intake, and it has been suggested that corticotropin-releasing hormone could mediate this response. The present study inve...

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Detalles Bibliográficos
Autores: Gastón, María Soledad, Cid, Mariana Paula, Salvatierra, Nancy Alicia
Formato: artículo
Fecha de Publicación:2021
Institución:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Lenguaje:español
OAI Identifier:oai:ojs.csi.unmsm:article/18810
Enlace del recurso:https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/18810
Nivel de acceso:acceso abierto
Materia:ghrelin
feed intake
corticosterone
forebrain
broiler
grelina
ingesta de alimentos
corticosterona
cerebro anterior
pollos domésticos
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network_name_str Revistas - Universidad Nacional Mayor de San Marcos
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spelling The anorexigenic effect of intra-mesopallium ghrelin is related to high plasma corticosterone levels in broiler chicks during the first week of lifeEl efecto anorexígeno de la grelina intra-mesopallium está relacionado con niveles elevados de corticosterona plasmática en pollos parrilleros durante la primera semana de vidaGastón, María SoledadCid, Mariana PaulaSalvatierra, Nancy AliciaGastón, María SoledadCid, Mariana PaulaSalvatierra, Nancy Aliciaghrelinfeed intakecorticosteroneforebrainbroilergrelinaingesta de alimentoscorticosteronacerebro anteriorpollos domésticosGhrelin is peptide secreted primarily in the stomach that acts on the central nervous system to regulate energy metabolism and responses to stress. In chicken, it decreases feed intake, and it has been suggested that corticotropin-releasing hormone could mediate this response. The present study investigates whether intra-mesopallium ghrelin-induced anorexia could involve the activation of the hypothalamic pituitary adrenal axis in 4-6-day-old chickens. The results showed that ghrelin, administered in the intermediate mesopallium, decreased feed intake and increased plasma corticosterone levels. In addition, a significant negative relationship was observed between both responses, where higher concentrations of corticosterone were associated with lower food intake. However, no significant changes were observed in plasma levels of ACTH induced by intra-mesopallium ghrelin. Therefore, this adrenal activation could play a mediating role in the anorectic effect of central ghrelin in broilers. Furthermore, it cannot be ruled out that this area of the forebrain and the hypothalamic pituitary adrenal axis may constitute a brain network for the control of chicken feeding.La grelina es principalmente un péptido secretado principalmente en el estómago que actúa sobre el sistema nervioso central para regular el metabolismo energético y las respuestas al estrés. En el pollo disminuye la ingesta de alimentos y se ha sugerido que la hormona liberadora de corticotropina podría mediar esta respuesta. En el presente estudio se estudia si la anorexia inducida por grelina intra-mesopallium podría involucrar la activación del eje hipotalámico pituitario adrenal en pollos de 4-6 días de edad. Los resultados demuestran que la grelina, administrada en el mesopallium intermedio, disminuyó la ingesta de alimentos y aumentó los niveles plasmáticos de corticosterona. Además, se observó una relación negativa significativa entre ambas respuestas, donde mayores concentraciones de corticosterona estuvieron asociadas a una menor ingesta de alimentos. Sin embargo, no se observaron cambios significativos en los niveles plasmáticos de la hormona adrenocorticótropa inducidos por la grelina intra-mesopallium. Por lo tanto, esta activación suprarrenal podría desempeñar un papel mediador en el efecto anorexigénico de la grelina central en pollos de engorde. Además, no puede descartarse que esta área del prosencéfalo y el eje hipotalámico pituitario adrenal puedan constituir una red cerebral para el control de la alimentación de pollos parrilleros.Universidad Nacional Mayor de San Marcos, Facultad de Medicina Veterinaria2021-06-23info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/1881010.15381/rivep.v32i3.18810Revista de Investigaciones Veterinarias del Perú; Vol. 32 Núm. 3 (2021); e18810Revista de Investigaciones Veterinarias del Perú; Vol. 32 No. 3 (2021); e188101682-34191609-9117reponame:Revistas - Universidad Nacional Mayor de San Marcosinstname:Universidad Nacional Mayor de San Marcosinstacron:UNMSMspahttps://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/18810/16807Derechos de autor 2021 María Soledad Gastón, Mariana Paula Cid, Nancy Alicia Salvatierrahttp://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessoai:ojs.csi.unmsm:article/188102021-06-25T10:16:44Z
dc.title.none.fl_str_mv The anorexigenic effect of intra-mesopallium ghrelin is related to high plasma corticosterone levels in broiler chicks during the first week of life
El efecto anorexígeno de la grelina intra-mesopallium está relacionado con niveles elevados de corticosterona plasmática en pollos parrilleros durante la primera semana de vida
title The anorexigenic effect of intra-mesopallium ghrelin is related to high plasma corticosterone levels in broiler chicks during the first week of life
spellingShingle The anorexigenic effect of intra-mesopallium ghrelin is related to high plasma corticosterone levels in broiler chicks during the first week of life
Gastón, María Soledad
ghrelin
feed intake
corticosterone
forebrain
broiler
grelina
ingesta de alimentos
corticosterona
cerebro anterior
pollos domésticos
title_short The anorexigenic effect of intra-mesopallium ghrelin is related to high plasma corticosterone levels in broiler chicks during the first week of life
title_full The anorexigenic effect of intra-mesopallium ghrelin is related to high plasma corticosterone levels in broiler chicks during the first week of life
title_fullStr The anorexigenic effect of intra-mesopallium ghrelin is related to high plasma corticosterone levels in broiler chicks during the first week of life
title_full_unstemmed The anorexigenic effect of intra-mesopallium ghrelin is related to high plasma corticosterone levels in broiler chicks during the first week of life
title_sort The anorexigenic effect of intra-mesopallium ghrelin is related to high plasma corticosterone levels in broiler chicks during the first week of life
dc.creator.none.fl_str_mv Gastón, María Soledad
Cid, Mariana Paula
Salvatierra, Nancy Alicia
Gastón, María Soledad
Cid, Mariana Paula
Salvatierra, Nancy Alicia
author Gastón, María Soledad
author_facet Gastón, María Soledad
Cid, Mariana Paula
Salvatierra, Nancy Alicia
author_role author
author2 Cid, Mariana Paula
Salvatierra, Nancy Alicia
author2_role author
author
dc.subject.none.fl_str_mv ghrelin
feed intake
corticosterone
forebrain
broiler
grelina
ingesta de alimentos
corticosterona
cerebro anterior
pollos domésticos
topic ghrelin
feed intake
corticosterone
forebrain
broiler
grelina
ingesta de alimentos
corticosterona
cerebro anterior
pollos domésticos
description Ghrelin is peptide secreted primarily in the stomach that acts on the central nervous system to regulate energy metabolism and responses to stress. In chicken, it decreases feed intake, and it has been suggested that corticotropin-releasing hormone could mediate this response. The present study investigates whether intra-mesopallium ghrelin-induced anorexia could involve the activation of the hypothalamic pituitary adrenal axis in 4-6-day-old chickens. The results showed that ghrelin, administered in the intermediate mesopallium, decreased feed intake and increased plasma corticosterone levels. In addition, a significant negative relationship was observed between both responses, where higher concentrations of corticosterone were associated with lower food intake. However, no significant changes were observed in plasma levels of ACTH induced by intra-mesopallium ghrelin. Therefore, this adrenal activation could play a mediating role in the anorectic effect of central ghrelin in broilers. Furthermore, it cannot be ruled out that this area of the forebrain and the hypothalamic pituitary adrenal axis may constitute a brain network for the control of chicken feeding.
publishDate 2021
dc.date.none.fl_str_mv 2021-06-23
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/18810
10.15381/rivep.v32i3.18810
url https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/18810
identifier_str_mv 10.15381/rivep.v32i3.18810
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/18810/16807
dc.rights.none.fl_str_mv Derechos de autor 2021 María Soledad Gastón, Mariana Paula Cid, Nancy Alicia Salvatierra
http://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Derechos de autor 2021 María Soledad Gastón, Mariana Paula Cid, Nancy Alicia Salvatierra
http://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Medicina Veterinaria
publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Medicina Veterinaria
dc.source.none.fl_str_mv Revista de Investigaciones Veterinarias del Perú; Vol. 32 Núm. 3 (2021); e18810
Revista de Investigaciones Veterinarias del Perú; Vol. 32 No. 3 (2021); e18810
1682-3419
1609-9117
reponame:Revistas - Universidad Nacional Mayor de San Marcos
instname:Universidad Nacional Mayor de San Marcos
instacron:UNMSM
instname_str Universidad Nacional Mayor de San Marcos
instacron_str UNMSM
institution UNMSM
reponame_str Revistas - Universidad Nacional Mayor de San Marcos
collection Revistas - Universidad Nacional Mayor de San Marcos
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 13.887938
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