Anti-inflammatory protective effect of cannabidiol extracted from Cannabis sativa L. (hemp) against SARS-CoV-2 infection: A review of the literature
Descripción del Articulo
Cannabidiol (CBD) is a non-psychotropic phytocannabinoid derived from cannabidiolic acid and has anti-inflammatory, analgesic, antineoplastic, and chemopreventive properties that even enhance the immune system thanks to the human endocannabinoid system. It is due to these characteristics that studie...
| Autores: | , , , , , , |
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| Formato: | artículo |
| Fecha de Publicación: | 2024 |
| Institución: | Universidad Nacional de Trujillo |
| Repositorio: | Revistas - Universidad Nacional de Trujillo |
| Lenguaje: | español |
| OAI Identifier: | oai:ojs.revistas.unitru.edu.pe:article/5713 |
| Enlace del recurso: | https://revistas.unitru.edu.pe/index.php/RMT/article/view/5713 |
| Nivel de acceso: | acceso abierto |
| Materia: | Cannabidiol COVID-19 Immune System Sistema Inmunológico |
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Anti-inflammatory protective effect of cannabidiol extracted from Cannabis sativa L. (hemp) against SARS-CoV-2 infection: A review of the literatureEfecto protector antiinflamatorio del cannabidiol extraído de Cannabis sativa L. (cáñamo) frente a infección por SARS-CoV-2: Una revisión de la literaturaLudeña-Meléndez, VictorJimenez-Alvarez, HaroldLaiza Pajilla, DannaIshikawa-Arias, PaulaGutiérrez-Guerrero, AnaLedesma Chavarria, LeonardoCampos-Reyna, Jorge LuisCannabidiolCOVID-19Immune SystemCannabidiolCOVID-19Sistema InmunológicoCannabidiol (CBD) is a non-psychotropic phytocannabinoid derived from cannabidiolic acid and has anti-inflammatory, analgesic, antineoplastic, and chemopreventive properties that even enhance the immune system thanks to the human endocannabinoid system. It is due to these characteristics that studies have been carried out to test its effectiveness as a treatment option against COVID-19, which meets the global medical goal of combating this disease since it became a pandemic in early 2020. CBD has been reported to have antiviral activity against the coronavirus, in addition to reducing the expression of the ACE-2 enzyme and the levels of proinflammatory cytokines, which results in structural and functional improvements of the tissues infected by SARS-CoV-2.El cannabidiol (CBD) es un fitocannabinoide no psicotrópico derivado del ácido cannabidiólico y posee propiedades antiinflamatorias, analgésicas, antineoplásicas y quimiopreventivas que llegan a potenciar incluso el sistema inmunológico gracias al sistema endocannabinoide humano, y es debido a estas características que se han realizado estudios para probar su efectividad como una opción de tratamiento frente a la COVID-19, lo cual responde al objetivo médico mundial de combatir esta enfermedad desde que se convirtió en una pandemia a inicios de 2020. Se ha reportado que el CBD presenta actividad antiviral contra el coronavirus, además de reducir la expresión de la enzima ECA-2 y los niveles de citocinas proinflamatorias, lo que resulta en mejoras estructurales y funcionales de los tejidos infectados por SARS-CoV-2.Facultad de Medicina2024-12-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistas.unitru.edu.pe/index.php/RMT/article/view/5713Revista Médica de Trujillo; Vol. 19 Núm. 4 (2024): REVISTA MÉDICA DE TRUJILLO; 126-1322522-6150reponame:Revistas - Universidad Nacional de Trujilloinstname:Universidad Nacional de Trujilloinstacron:UNITRUspahttps://revistas.unitru.edu.pe/index.php/RMT/article/view/5713/6294Derechos de autor 2024 "Los autores conservarán sus derechos de autor y garantizarán a la revista el derecho de primera publicación de su obra"https://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccessoai:ojs.revistas.unitru.edu.pe:article/57132025-01-01T00:06:22Z |
| dc.title.none.fl_str_mv |
Anti-inflammatory protective effect of cannabidiol extracted from Cannabis sativa L. (hemp) against SARS-CoV-2 infection: A review of the literature Efecto protector antiinflamatorio del cannabidiol extraído de Cannabis sativa L. (cáñamo) frente a infección por SARS-CoV-2: Una revisión de la literatura |
| title |
Anti-inflammatory protective effect of cannabidiol extracted from Cannabis sativa L. (hemp) against SARS-CoV-2 infection: A review of the literature |
| spellingShingle |
Anti-inflammatory protective effect of cannabidiol extracted from Cannabis sativa L. (hemp) against SARS-CoV-2 infection: A review of the literature Ludeña-Meléndez, Victor Cannabidiol COVID-19 Immune System Cannabidiol COVID-19 Sistema Inmunológico |
| title_short |
Anti-inflammatory protective effect of cannabidiol extracted from Cannabis sativa L. (hemp) against SARS-CoV-2 infection: A review of the literature |
| title_full |
Anti-inflammatory protective effect of cannabidiol extracted from Cannabis sativa L. (hemp) against SARS-CoV-2 infection: A review of the literature |
| title_fullStr |
Anti-inflammatory protective effect of cannabidiol extracted from Cannabis sativa L. (hemp) against SARS-CoV-2 infection: A review of the literature |
| title_full_unstemmed |
Anti-inflammatory protective effect of cannabidiol extracted from Cannabis sativa L. (hemp) against SARS-CoV-2 infection: A review of the literature |
| title_sort |
Anti-inflammatory protective effect of cannabidiol extracted from Cannabis sativa L. (hemp) against SARS-CoV-2 infection: A review of the literature |
| dc.creator.none.fl_str_mv |
Ludeña-Meléndez, Victor Jimenez-Alvarez, Harold Laiza Pajilla, Danna Ishikawa-Arias, Paula Gutiérrez-Guerrero, Ana Ledesma Chavarria, Leonardo Campos-Reyna, Jorge Luis |
| author |
Ludeña-Meléndez, Victor |
| author_facet |
Ludeña-Meléndez, Victor Jimenez-Alvarez, Harold Laiza Pajilla, Danna Ishikawa-Arias, Paula Gutiérrez-Guerrero, Ana Ledesma Chavarria, Leonardo Campos-Reyna, Jorge Luis |
| author_role |
author |
| author2 |
Jimenez-Alvarez, Harold Laiza Pajilla, Danna Ishikawa-Arias, Paula Gutiérrez-Guerrero, Ana Ledesma Chavarria, Leonardo Campos-Reyna, Jorge Luis |
| author2_role |
author author author author author author |
| dc.subject.none.fl_str_mv |
Cannabidiol COVID-19 Immune System Cannabidiol COVID-19 Sistema Inmunológico |
| topic |
Cannabidiol COVID-19 Immune System Cannabidiol COVID-19 Sistema Inmunológico |
| description |
Cannabidiol (CBD) is a non-psychotropic phytocannabinoid derived from cannabidiolic acid and has anti-inflammatory, analgesic, antineoplastic, and chemopreventive properties that even enhance the immune system thanks to the human endocannabinoid system. It is due to these characteristics that studies have been carried out to test its effectiveness as a treatment option against COVID-19, which meets the global medical goal of combating this disease since it became a pandemic in early 2020. CBD has been reported to have antiviral activity against the coronavirus, in addition to reducing the expression of the ACE-2 enzyme and the levels of proinflammatory cytokines, which results in structural and functional improvements of the tissues infected by SARS-CoV-2. |
| publishDate |
2024 |
| dc.date.none.fl_str_mv |
2024-12-31 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
https://revistas.unitru.edu.pe/index.php/RMT/article/view/5713 |
| url |
https://revistas.unitru.edu.pe/index.php/RMT/article/view/5713 |
| dc.language.none.fl_str_mv |
spa |
| language |
spa |
| dc.relation.none.fl_str_mv |
https://revistas.unitru.edu.pe/index.php/RMT/article/view/5713/6294 |
| dc.rights.none.fl_str_mv |
https://creativecommons.org/licenses/by-nc/4.0/ info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by-nc/4.0/ |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
application/pdf |
| dc.publisher.none.fl_str_mv |
Facultad de Medicina |
| publisher.none.fl_str_mv |
Facultad de Medicina |
| dc.source.none.fl_str_mv |
Revista Médica de Trujillo; Vol. 19 Núm. 4 (2024): REVISTA MÉDICA DE TRUJILLO; 126-132 2522-6150 reponame:Revistas - Universidad Nacional de Trujillo instname:Universidad Nacional de Trujillo instacron:UNITRU |
| instname_str |
Universidad Nacional de Trujillo |
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UNITRU |
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UNITRU |
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Revistas - Universidad Nacional de Trujillo |
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Revistas - Universidad Nacional de Trujillo |
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Nota importante:
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).
