Amyloidosis cardiomyopathy: an unforeseen cause of stroke

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A 57-year-old male with a history of peripheral neuropathy and dyspnea for one year of evolution was admitted for ischemic stroke. Electrocardiographic and ultrasound studies revealed underlying hypertrophic cardiomyopathy.The electrophoretic proteinogram and immunofixation showed that it was a mono...

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Detalles Bibliográficos
Autores: Lazo-Soldevilla, Marco, Meza- Centeno, Lizeth, Santos-Julca, Carmen, Maita-Hinostroza, Richard
Formato: artículo
Fecha de Publicación:2022
Institución:Sociedad Peruana de Medicina Interna
Repositorio:Revista de la Sociedad Peruana de Medicina Interna
Lenguaje:español
OAI Identifier:oai:medicinainterna.net.pe:article/655
Enlace del recurso:https://revistamedicinainterna.net/index.php/spmi/article/view/655
Nivel de acceso:acceso abierto
Materia:accidente cerebrovascular isquémico
miocardiopatía infiltrativa
amiloidosis cardiaca
cadenas ligeras
GMUS
ischemic stroke
infiltrative cardiomyopathy
cardiac amyloidosis
light chains
Descripción
Sumario:A 57-year-old male with a history of peripheral neuropathy and dyspnea for one year of evolution was admitted for ischemic stroke. Electrocardiographic and ultrasound studies revealed underlying hypertrophic cardiomyopathy.The electrophoretic proteinogram and immunofixation showed that it was a monoclonal gammopathy by lambda-light chains. Biopsy of gingival mucosa demonstrated and bone marrow the presence of amyloidosis. It was concluded that it was a cardiac of light chains amyloidosis secondary to monoclonal gammopathy of uncertain significance GMUS.The patient received chemotherapy but died two months after admission.
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