The deferral and relapse`s time post induction chemotherapy in children with acute lymphoblastic leukemia at a National Hospital in Lambayeque

• Autores: Tafur-Hoyos, Brenda Aurora Dolores, Burga-Guevara, Diana Katherine, Sánchez-Neira, Carlos, Díaz-Silva, Víctor Hugo
• Formato: artículo
• Fecha de Publicación: 2022
• Institución: Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
• Repositorio: Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
• Lenguaje: español
• OAI Identifier: oai:cmhnaaa_ojs_cmhnaaa.cmhnaaa.org.pe:article/1097
• Enlace del recurso: https://cmhnaaa.org.pe/ojs/index.php/rcmhnaaa/article/view/1097
• Nivel de acceso: acceso abierto
• Materia: Leucemia Linfoblástica Aguda; Recaída; Quimioterapia; Leukemia acute lymphoblastic; Recurrence; Chemotherapy

Objetive: To know the delay and relapse time after induction chemotherapy in children with acute lymphoblastic leukemia (ALL) in a national hospital in Lambayeque. The study: Analytical observational study of a retrospective cohort. The medical records of patients whose age is 2 and 15 years with diagnosis of ALL who achieved complete remission at the end of induction treated and a national hospital in Lambayeque ,were reviewed. Findings: The patients studied had a median age of 5 years. Although the majority responded at the end of IA induction, still 43/75 children with ALL relapsed. Children with relapse had a delay of 6 days [IQR: 0-25] between the end of induction and the beginning of the consolidation phase. Conclusion: Delay ≥7 days in chemotherapy regimens affects the sustainability of remission.