Loop-mediated isothermal DNA amplification for asymptomatic malaria detection in challenging field settings: Technical performance and pilot implementation in the Peruvian Amazon

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Loop-mediated isothermal DNA amplification (LAMP) methodology offers an opportunity for point-of-care (POC) molecular detection of asymptomatic malaria infections. However, there is still little evidence on the feasibility of implementing this technique for population screenings in isolated field se...

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Detalles Bibliográficos
Autores: Serra-Casas E., Manrique P., Ding X.C., Carrasco-Escobar G., Alava F., Gave A., Rodriguez H., Contreras-Mancilla J., Rosas-Aguirre A., Speybroeck N., González I.J., Rosanas-Urgell A., Gamboa D.
Formato: artículo
Fecha de Publicación:2017
Institución:Consejo Nacional de Ciencia Tecnología e Innovación
Repositorio:CONCYTEC-Institucional
Lenguaje:inglés
OAI Identifier:oai:repositorio.concytec.gob.pe:20.500.12390/678
Enlace del recurso:https://hdl.handle.net/20.500.12390/678
https://doi.org/10.1371/journal.pone.0185742
Nivel de acceso:acceso abierto
Materia:protozoal DNA
adolescent
adult
Amazon
Article
asymptomatic disease
bright field microscopy
child
controlled clinical trial
controlled study
cross-sectional study
density
diagnostic accuracy
diagnostic kit
diagnostic test accuracy study
diagnostic value
disease carrier
DNA determination
feasibility study
female
field study
gene amplification
human
intermethod comparison
loop mediated isothermal amplification
major clinical study
malaria
malaria falciparum
male
mass screening
mixed infection
molecular diagnosis
parasite density
parasite identification
Peru
https://purl.org/pe-repo/ocde/ford#3.03.12
id CONC_5082059e312adcfad16ba6c90595aa55
oai_identifier_str oai:repositorio.concytec.gob.pe:20.500.12390/678
network_acronym_str CONC
network_name_str CONCYTEC-Institucional
repository_id_str 4689
dc.title.none.fl_str_mv Loop-mediated isothermal DNA amplification for asymptomatic malaria detection in challenging field settings: Technical performance and pilot implementation in the Peruvian Amazon
title Loop-mediated isothermal DNA amplification for asymptomatic malaria detection in challenging field settings: Technical performance and pilot implementation in the Peruvian Amazon
spellingShingle Loop-mediated isothermal DNA amplification for asymptomatic malaria detection in challenging field settings: Technical performance and pilot implementation in the Peruvian Amazon
Serra-Casas E.
protozoal DNA
adolescent
adult
Amazon
Article
asymptomatic disease
bright field microscopy
child
controlled clinical trial
controlled study
cross-sectional study
density
diagnostic accuracy
diagnostic kit
diagnostic test accuracy study
diagnostic value
disease carrier
DNA determination
feasibility study
female
field study
gene amplification
human
intermethod comparison
loop mediated isothermal amplification
major clinical study
malaria
malaria falciparum
male
mass screening
mixed infection
molecular diagnosis
parasite density
parasite identification
Peru
https://purl.org/pe-repo/ocde/ford#3.03.12
title_short Loop-mediated isothermal DNA amplification for asymptomatic malaria detection in challenging field settings: Technical performance and pilot implementation in the Peruvian Amazon
title_full Loop-mediated isothermal DNA amplification for asymptomatic malaria detection in challenging field settings: Technical performance and pilot implementation in the Peruvian Amazon
title_fullStr Loop-mediated isothermal DNA amplification for asymptomatic malaria detection in challenging field settings: Technical performance and pilot implementation in the Peruvian Amazon
title_full_unstemmed Loop-mediated isothermal DNA amplification for asymptomatic malaria detection in challenging field settings: Technical performance and pilot implementation in the Peruvian Amazon
title_sort Loop-mediated isothermal DNA amplification for asymptomatic malaria detection in challenging field settings: Technical performance and pilot implementation in the Peruvian Amazon
author Serra-Casas E.
author_facet Serra-Casas E.
Manrique P.
Ding X.C.
Carrasco-Escobar G.
Alava F.
Gave A.
Rodriguez H.
Contreras-Mancilla J.
Rosas-Aguirre A.
Speybroeck N.
González I.J.
Rosanas-Urgell A.
Gamboa D.
author_role author
author2 Manrique P.
Ding X.C.
Carrasco-Escobar G.
Alava F.
Gave A.
Rodriguez H.
Contreras-Mancilla J.
Rosas-Aguirre A.
Speybroeck N.
González I.J.
Rosanas-Urgell A.
Gamboa D.
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Serra-Casas E.
Manrique P.
Ding X.C.
Carrasco-Escobar G.
Alava F.
Gave A.
Rodriguez H.
Contreras-Mancilla J.
Rosas-Aguirre A.
Speybroeck N.
González I.J.
Rosanas-Urgell A.
Gamboa D.
dc.subject.none.fl_str_mv protozoal DNA
topic protozoal DNA
adolescent
adult
Amazon
Article
asymptomatic disease
bright field microscopy
child
controlled clinical trial
controlled study
cross-sectional study
density
diagnostic accuracy
diagnostic kit
diagnostic test accuracy study
diagnostic value
disease carrier
DNA determination
feasibility study
female
field study
gene amplification
human
intermethod comparison
loop mediated isothermal amplification
major clinical study
malaria
malaria falciparum
male
mass screening
mixed infection
molecular diagnosis
parasite density
parasite identification
Peru
https://purl.org/pe-repo/ocde/ford#3.03.12
dc.subject.es_PE.fl_str_mv adolescent
adult
Amazon
Article
asymptomatic disease
bright field microscopy
child
controlled clinical trial
controlled study
cross-sectional study
density
diagnostic accuracy
diagnostic kit
diagnostic test accuracy study
diagnostic value
disease carrier
DNA determination
feasibility study
female
field study
gene amplification
human
intermethod comparison
loop mediated isothermal amplification
major clinical study
malaria
malaria falciparum
male
mass screening
mixed infection
molecular diagnosis
parasite density
parasite identification
Peru
dc.subject.ocde.none.fl_str_mv https://purl.org/pe-repo/ocde/ford#3.03.12
description Loop-mediated isothermal DNA amplification (LAMP) methodology offers an opportunity for point-of-care (POC) molecular detection of asymptomatic malaria infections. However, there is still little evidence on the feasibility of implementing this technique for population screenings in isolated field settings.
publishDate 2017
dc.date.accessioned.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.available.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.issued.fl_str_mv 2017
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12390/678
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1371/journal.pone.0185742
dc.identifier.scopus.none.fl_str_mv 2-s2.0-85030676412
url https://hdl.handle.net/20.500.12390/678
https://doi.org/10.1371/journal.pone.0185742
identifier_str_mv 2-s2.0-85030676412
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv PLoS ONE
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.uri.none.fl_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
dc.source.none.fl_str_mv reponame:CONCYTEC-Institucional
instname:Consejo Nacional de Ciencia Tecnología e Innovación
instacron:CONCYTEC
instname_str Consejo Nacional de Ciencia Tecnología e Innovación
instacron_str CONCYTEC
institution CONCYTEC
reponame_str CONCYTEC-Institucional
collection CONCYTEC-Institucional
repository.name.fl_str_mv Repositorio Institucional CONCYTEC
repository.mail.fl_str_mv repositorio@concytec.gob.pe
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However, there is still little evidence on the feasibility of implementing this technique for population screenings in isolated field settings.Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - ConcytecengPublic Library of SciencePLoS ONEinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/4.0/protozoal DNAadolescent-1adult-1Amazon-1Article-1asymptomatic disease-1bright field microscopy-1child-1controlled clinical trial-1controlled study-1cross-sectional study-1density-1diagnostic accuracy-1diagnostic kit-1diagnostic test accuracy study-1diagnostic value-1disease carrier-1DNA determination-1feasibility study-1female-1field study-1gene amplification-1human-1intermethod comparison-1loop mediated isothermal amplification-1major clinical study-1malaria-1malaria falciparum-1male-1mass screening-1mixed infection-1molecular diagnosis-1parasite density-1parasite identification-1Peru-1https://purl.org/pe-repo/ocde/ford#3.03.12-1Loop-mediated isothermal 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<DisplayName>Public Library of Science</DisplayName> <OrgUnit /> </Publisher> </Publishers> <License>https://creativecommons.org/licenses/by-nc-nd/4.0/</License> <Keyword>protozoal DNA</Keyword> <Keyword>adolescent</Keyword> <Keyword>adult</Keyword> <Keyword>Amazon</Keyword> <Keyword>Article</Keyword> <Keyword>asymptomatic disease</Keyword> <Keyword>bright field microscopy</Keyword> <Keyword>child</Keyword> <Keyword>controlled clinical trial</Keyword> <Keyword>controlled study</Keyword> <Keyword>cross-sectional study</Keyword> <Keyword>density</Keyword> <Keyword>diagnostic accuracy</Keyword> <Keyword>diagnostic kit</Keyword> <Keyword>diagnostic test accuracy study</Keyword> <Keyword>diagnostic value</Keyword> <Keyword>disease carrier</Keyword> <Keyword>DNA determination</Keyword> <Keyword>feasibility study</Keyword> <Keyword>female</Keyword> <Keyword>field study</Keyword> <Keyword>gene amplification</Keyword> <Keyword>human</Keyword> <Keyword>intermethod comparison</Keyword> <Keyword>loop mediated isothermal amplification</Keyword> <Keyword>major clinical study</Keyword> <Keyword>malaria</Keyword> <Keyword>malaria falciparum</Keyword> <Keyword>male</Keyword> <Keyword>mass screening</Keyword> <Keyword>mixed infection</Keyword> <Keyword>molecular diagnosis</Keyword> <Keyword>parasite density</Keyword> <Keyword>parasite identification</Keyword> <Keyword>Peru</Keyword> <Abstract>Loop-mediated isothermal DNA amplification (LAMP) methodology offers an opportunity for point-of-care (POC) molecular detection of asymptomatic malaria infections. 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La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).