Alteration in the phagocyte activity of crevicular leucocytes regarding diabetic patients with periodontal disease

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The goal of this investigation was to find out the alterations in the phagocyte activity of crevicular leucocytes regarding to diabetic patients with periodontal disease. For that reason, 56 patients with periodontal disease were selected: 42 of them with a diagnosis of Diabetes Mellitus - Type 2, a...

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Autor: Colchado Carhuavilca, Jorge R.
Formato: artículo
Fecha de Publicación:2008
Institución:Universidad Nacional Mayor de San Marcos
Repositorio:Revista UNMSM - Odontología Sanmarquina
Lenguaje:español
OAI Identifier:oai:ojs.csi.unmsm:article/3072
Enlace del recurso:https://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/3072
Nivel de acceso:acceso abierto
Materia:Diabetes
crevice fluid
fagocitosis
leukocytic adherence
periodontal disease.
leukocytes
adherence
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spelling Alteration in the phagocyte activity of crevicular leucocytes regarding diabetic patients with periodontal diseaseAlteraciones en la fagocitosis de los leucocitos creviculares de pacientes diabéticos con enfermedad periodontalColchado Carhuavilca, Jorge R.Diabetescrevice fluidfagocitosisleukocytic adherenceperiodontal disease.Diabetescrevice fluidfagocitosisleukocytesadherenceperiodontal disease.The goal of this investigation was to find out the alterations in the phagocyte activity of crevicular leucocytes regarding to diabetic patients with periodontal disease. For that reason, 56 patients with periodontal disease were selected: 42 of them with a diagnosis of Diabetes Mellitus - Type 2, and 14 patients without it (control group), from 35 to 74 years old. To performed the study, crevicular fluid of the mentioned patients was analyzed. By means of sequential washings the samples were analyzed microbiological and inmunologically, taking Candida albicans ATCC as indicator of the phagocyte activity. It was found that only a mean of 22.02 (± 7.62) of diabetics crevicular leucocytes group have an adequate phagocyte activity compared to 78.64 (± 9.20) of control group. In the same manner a mean of 78.21 (± 7.84) of diabetics crevicular leucocytes group made adherence without ingestion of C.a. compared to only 21.36 (± 9.20) of the control group. The differences between appropriated phagocytosis and ingestion activity of C.a. diabetics’ crevicular leukocytes group and phagocytes of control group were statistical significant, t = 15.5 (p <=0.001), in the same manner the differences between leukocyte adherence without ingestion of C.a. of diabetic group and the control group, were statistical significant, t = 15.4(p <=0.001).El objetivo de la presente investigación fue determinar la existencia de alteraciones en la fagocitosis de los leucocitos creviculares de pacientes diabéticos con Enfermedad Periodontal. Para tal efecto, se seleccionaron 56 individuos con Enfermedad Periodontal: 42 pacientes con diagnóstico de Diabetes Mellitus tipo 2 y 14 sin ella (grupo control), comprendidos entre 35 y 74 años de edad. Para la realización del estudio, se tomó como unidad de análisis los leucocitos provenientes del fluido crevicular de los pacientes en mención. Mediante lavados secuenciales; las muestras fueron analizadas microbiológica e inmunológicamente, teniendo como indicador, de la actividad fagocítica, a la Candida albicans ATCC. Hallándose que sólo el 22,02 (±7,62) de los leucocitos creviculares de diabéticos realiza una adecuada actividad fagocítica frente al 78,64 (±9,20) del grupo control. Asimismo el 78,21 (± 7,84) de los leucocitos creviculares de diabéticos realiza la adherencia leucocitaria sin ingesta del patógeno frente a un 21,36 (± 9,20) del grupo control. Resultando diferencias estadísticamente significativas en la adecuada fagocitosis del grupo de leucocitos creviculares de los diabéticos en relación al grupo control con un valor t= 15,5 (p <=0,001), del mismo modo las diferencias estadísticas fueron significativas en relación de la adherencia leucocitaria sin ingesta del patógeno con un valor t= 15,4 (p<=0,001) referente a los leucocitos creviculares de los pacientes diabéticos frente al grupo control.Universidad Nacional Mayor de San Marcos, Facultad de Odontología2008-07-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/307210.15381/os.v11i1.3072Odontología Sanmarquina; Vol 11 No 1 (2008); 14-18Odontología Sanmarquina; Vol. 11 Núm. 1 (2008); 14-181609-86171560-9111reponame:Revista UNMSM - Odontología Sanmarquinainstname:Universidad Nacional Mayor de San Marcosinstacron:UNMSMspahttps://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/3072/2583Derechos de autor 2008 Jorge R. Colchado Carhuavilcahttp://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccess2021-06-01T17:15:46Zmail@mail.com -
dc.title.none.fl_str_mv Alteration in the phagocyte activity of crevicular leucocytes regarding diabetic patients with periodontal disease
Alteraciones en la fagocitosis de los leucocitos creviculares de pacientes diabéticos con enfermedad periodontal
title Alteration in the phagocyte activity of crevicular leucocytes regarding diabetic patients with periodontal disease
spellingShingle Alteration in the phagocyte activity of crevicular leucocytes regarding diabetic patients with periodontal disease
Colchado Carhuavilca, Jorge R.
Diabetes
crevice fluid
fagocitosis
leukocytic adherence
periodontal disease.
Diabetes
crevice fluid
fagocitosis
leukocytes
adherence
periodontal disease.
title_short Alteration in the phagocyte activity of crevicular leucocytes regarding diabetic patients with periodontal disease
title_full Alteration in the phagocyte activity of crevicular leucocytes regarding diabetic patients with periodontal disease
title_fullStr Alteration in the phagocyte activity of crevicular leucocytes regarding diabetic patients with periodontal disease
title_full_unstemmed Alteration in the phagocyte activity of crevicular leucocytes regarding diabetic patients with periodontal disease
title_sort Alteration in the phagocyte activity of crevicular leucocytes regarding diabetic patients with periodontal disease
dc.creator.none.fl_str_mv Colchado Carhuavilca, Jorge R.
author Colchado Carhuavilca, Jorge R.
author_facet Colchado Carhuavilca, Jorge R.
author_role author
dc.subject.none.fl_str_mv Diabetes
crevice fluid
fagocitosis
leukocytic adherence
periodontal disease.
Diabetes
crevice fluid
fagocitosis
leukocytes
adherence
periodontal disease.
topic Diabetes
crevice fluid
fagocitosis
leukocytic adherence
periodontal disease.
Diabetes
crevice fluid
fagocitosis
leukocytes
adherence
periodontal disease.
dc.description.none.fl_txt_mv The goal of this investigation was to find out the alterations in the phagocyte activity of crevicular leucocytes regarding to diabetic patients with periodontal disease. For that reason, 56 patients with periodontal disease were selected: 42 of them with a diagnosis of Diabetes Mellitus - Type 2, and 14 patients without it (control group), from 35 to 74 years old. To performed the study, crevicular fluid of the mentioned patients was analyzed. By means of sequential washings the samples were analyzed microbiological and inmunologically, taking Candida albicans ATCC as indicator of the phagocyte activity. It was found that only a mean of 22.02 (± 7.62) of diabetics crevicular leucocytes group have an adequate phagocyte activity compared to 78.64 (± 9.20) of control group. In the same manner a mean of 78.21 (± 7.84) of diabetics crevicular leucocytes group made adherence without ingestion of C.a. compared to only 21.36 (± 9.20) of the control group. The differences between appropriated phagocytosis and ingestion activity of C.a. diabetics’ crevicular leukocytes group and phagocytes of control group were statistical significant, t = 15.5 (p <=0.001), in the same manner the differences between leukocyte adherence without ingestion of C.a. of diabetic group and the control group, were statistical significant, t = 15.4(p <=0.001).
El objetivo de la presente investigación fue determinar la existencia de alteraciones en la fagocitosis de los leucocitos creviculares de pacientes diabéticos con Enfermedad Periodontal. Para tal efecto, se seleccionaron 56 individuos con Enfermedad Periodontal: 42 pacientes con diagnóstico de Diabetes Mellitus tipo 2 y 14 sin ella (grupo control), comprendidos entre 35 y 74 años de edad. Para la realización del estudio, se tomó como unidad de análisis los leucocitos provenientes del fluido crevicular de los pacientes en mención. Mediante lavados secuenciales; las muestras fueron analizadas microbiológica e inmunológicamente, teniendo como indicador, de la actividad fagocítica, a la Candida albicans ATCC. Hallándose que sólo el 22,02 (±7,62) de los leucocitos creviculares de diabéticos realiza una adecuada actividad fagocítica frente al 78,64 (±9,20) del grupo control. Asimismo el 78,21 (± 7,84) de los leucocitos creviculares de diabéticos realiza la adherencia leucocitaria sin ingesta del patógeno frente a un 21,36 (± 9,20) del grupo control. Resultando diferencias estadísticamente significativas en la adecuada fagocitosis del grupo de leucocitos creviculares de los diabéticos en relación al grupo control con un valor t= 15,5 (p <=0,001), del mismo modo las diferencias estadísticas fueron significativas en relación de la adherencia leucocitaria sin ingesta del patógeno con un valor t= 15,4 (p<=0,001) referente a los leucocitos creviculares de los pacientes diabéticos frente al grupo control.
description The goal of this investigation was to find out the alterations in the phagocyte activity of crevicular leucocytes regarding to diabetic patients with periodontal disease. For that reason, 56 patients with periodontal disease were selected: 42 of them with a diagnosis of Diabetes Mellitus - Type 2, and 14 patients without it (control group), from 35 to 74 years old. To performed the study, crevicular fluid of the mentioned patients was analyzed. By means of sequential washings the samples were analyzed microbiological and inmunologically, taking Candida albicans ATCC as indicator of the phagocyte activity. It was found that only a mean of 22.02 (± 7.62) of diabetics crevicular leucocytes group have an adequate phagocyte activity compared to 78.64 (± 9.20) of control group. In the same manner a mean of 78.21 (± 7.84) of diabetics crevicular leucocytes group made adherence without ingestion of C.a. compared to only 21.36 (± 9.20) of the control group. The differences between appropriated phagocytosis and ingestion activity of C.a. diabetics’ crevicular leukocytes group and phagocytes of control group were statistical significant, t = 15.5 (p <=0.001), in the same manner the differences between leukocyte adherence without ingestion of C.a. of diabetic group and the control group, were statistical significant, t = 15.4(p <=0.001).
publishDate 2008
dc.date.none.fl_str_mv 2008-07-15
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/3072
10.15381/os.v11i1.3072
url https://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/3072
identifier_str_mv 10.15381/os.v11i1.3072
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/3072/2583
dc.rights.none.fl_str_mv Derechos de autor 2008 Jorge R. Colchado Carhuavilca
http://creativecommons.org/licenses/by-nc-sa/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Derechos de autor 2008 Jorge R. Colchado Carhuavilca
http://creativecommons.org/licenses/by-nc-sa/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Odontología
publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Odontología
dc.source.none.fl_str_mv Odontología Sanmarquina; Vol 11 No 1 (2008); 14-18
Odontología Sanmarquina; Vol. 11 Núm. 1 (2008); 14-18
1609-8617
1560-9111
reponame:Revista UNMSM - Odontología Sanmarquina
instname:Universidad Nacional Mayor de San Marcos
instacron:UNMSM
reponame_str Revista UNMSM - Odontología Sanmarquina
collection Revista UNMSM - Odontología Sanmarquina
instname_str Universidad Nacional Mayor de San Marcos
instacron_str UNMSM
institution UNMSM
repository.name.fl_str_mv -
repository.mail.fl_str_mv mail@mail.com
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score 13.977305
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