Alteration in the phagocyte activity of crevicular leucocytes regarding diabetic patients with periodontal disease
Descripción del Articulo
The goal of this investigation was to find out the alterations in the phagocyte activity of crevicular leucocytes regarding to diabetic patients with periodontal disease. For that reason, 56 patients with periodontal disease were selected: 42 of them with a diagnosis of Diabetes Mellitus - Type 2, a...
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|---|---|
| Formato: | artículo |
| Fecha de Publicación: | 2008 |
| Institución: | Universidad Nacional Mayor de San Marcos |
| Repositorio: | Revista UNMSM - Odontología Sanmarquina |
| Lenguaje: | español |
| OAI Identifier: | oai:ojs.csi.unmsm:article/3072 |
| Enlace del recurso: | https://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/3072 |
| Nivel de acceso: | acceso abierto |
| Materia: | Diabetes crevice fluid fagocitosis leukocytic adherence periodontal disease. leukocytes adherence |
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Revista UNMSM - Odontología Sanmarquina |
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Alteration in the phagocyte activity of crevicular leucocytes regarding diabetic patients with periodontal diseaseAlteraciones en la fagocitosis de los leucocitos creviculares de pacientes diabéticos con enfermedad periodontalColchado Carhuavilca, Jorge R.Diabetescrevice fluidfagocitosisleukocytic adherenceperiodontal disease.Diabetescrevice fluidfagocitosisleukocytesadherenceperiodontal disease.The goal of this investigation was to find out the alterations in the phagocyte activity of crevicular leucocytes regarding to diabetic patients with periodontal disease. For that reason, 56 patients with periodontal disease were selected: 42 of them with a diagnosis of Diabetes Mellitus - Type 2, and 14 patients without it (control group), from 35 to 74 years old. To performed the study, crevicular fluid of the mentioned patients was analyzed. By means of sequential washings the samples were analyzed microbiological and inmunologically, taking Candida albicans ATCC as indicator of the phagocyte activity. It was found that only a mean of 22.02 (± 7.62) of diabetics crevicular leucocytes group have an adequate phagocyte activity compared to 78.64 (± 9.20) of control group. In the same manner a mean of 78.21 (± 7.84) of diabetics crevicular leucocytes group made adherence without ingestion of C.a. compared to only 21.36 (± 9.20) of the control group. The differences between appropriated phagocytosis and ingestion activity of C.a. diabetics’ crevicular leukocytes group and phagocytes of control group were statistical significant, t = 15.5 (p <=0.001), in the same manner the differences between leukocyte adherence without ingestion of C.a. of diabetic group and the control group, were statistical significant, t = 15.4(p <=0.001).El objetivo de la presente investigación fue determinar la existencia de alteraciones en la fagocitosis de los leucocitos creviculares de pacientes diabéticos con Enfermedad Periodontal. Para tal efecto, se seleccionaron 56 individuos con Enfermedad Periodontal: 42 pacientes con diagnóstico de Diabetes Mellitus tipo 2 y 14 sin ella (grupo control), comprendidos entre 35 y 74 años de edad. Para la realización del estudio, se tomó como unidad de análisis los leucocitos provenientes del fluido crevicular de los pacientes en mención. Mediante lavados secuenciales; las muestras fueron analizadas microbiológica e inmunológicamente, teniendo como indicador, de la actividad fagocítica, a la Candida albicans ATCC. Hallándose que sólo el 22,02 (±7,62) de los leucocitos creviculares de diabéticos realiza una adecuada actividad fagocítica frente al 78,64 (±9,20) del grupo control. Asimismo el 78,21 (± 7,84) de los leucocitos creviculares de diabéticos realiza la adherencia leucocitaria sin ingesta del patógeno frente a un 21,36 (± 9,20) del grupo control. Resultando diferencias estadísticamente significativas en la adecuada fagocitosis del grupo de leucocitos creviculares de los diabéticos en relación al grupo control con un valor t= 15,5 (p <=0,001), del mismo modo las diferencias estadísticas fueron significativas en relación de la adherencia leucocitaria sin ingesta del patógeno con un valor t= 15,4 (p<=0,001) referente a los leucocitos creviculares de los pacientes diabéticos frente al grupo control.Universidad Nacional Mayor de San Marcos, Facultad de Odontología2008-07-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/307210.15381/os.v11i1.3072Odontología Sanmarquina; Vol 11 No 1 (2008); 14-18Odontología Sanmarquina; Vol. 11 Núm. 1 (2008); 14-181609-86171560-9111reponame:Revista UNMSM - Odontología Sanmarquinainstname:Universidad Nacional Mayor de San Marcosinstacron:UNMSMspahttps://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/3072/2583Derechos de autor 2008 Jorge R. Colchado Carhuavilcahttp://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccess2021-06-01T17:15:46Zmail@mail.com - |
| dc.title.none.fl_str_mv |
Alteration in the phagocyte activity of crevicular leucocytes regarding diabetic patients with periodontal disease Alteraciones en la fagocitosis de los leucocitos creviculares de pacientes diabéticos con enfermedad periodontal |
| title |
Alteration in the phagocyte activity of crevicular leucocytes regarding diabetic patients with periodontal disease |
| spellingShingle |
Alteration in the phagocyte activity of crevicular leucocytes regarding diabetic patients with periodontal disease Colchado Carhuavilca, Jorge R. Diabetes crevice fluid fagocitosis leukocytic adherence periodontal disease. Diabetes crevice fluid fagocitosis leukocytes adherence periodontal disease. |
| title_short |
Alteration in the phagocyte activity of crevicular leucocytes regarding diabetic patients with periodontal disease |
| title_full |
Alteration in the phagocyte activity of crevicular leucocytes regarding diabetic patients with periodontal disease |
| title_fullStr |
Alteration in the phagocyte activity of crevicular leucocytes regarding diabetic patients with periodontal disease |
| title_full_unstemmed |
Alteration in the phagocyte activity of crevicular leucocytes regarding diabetic patients with periodontal disease |
| title_sort |
Alteration in the phagocyte activity of crevicular leucocytes regarding diabetic patients with periodontal disease |
| dc.creator.none.fl_str_mv |
Colchado Carhuavilca, Jorge R. |
| author |
Colchado Carhuavilca, Jorge R. |
| author_facet |
Colchado Carhuavilca, Jorge R. |
| author_role |
author |
| dc.subject.none.fl_str_mv |
Diabetes crevice fluid fagocitosis leukocytic adherence periodontal disease. Diabetes crevice fluid fagocitosis leukocytes adherence periodontal disease. |
| topic |
Diabetes crevice fluid fagocitosis leukocytic adherence periodontal disease. Diabetes crevice fluid fagocitosis leukocytes adherence periodontal disease. |
| dc.description.none.fl_txt_mv |
The goal of this investigation was to find out the alterations in the phagocyte activity of crevicular leucocytes regarding to diabetic patients with periodontal disease. For that reason, 56 patients with periodontal disease were selected: 42 of them with a diagnosis of Diabetes Mellitus - Type 2, and 14 patients without it (control group), from 35 to 74 years old. To performed the study, crevicular fluid of the mentioned patients was analyzed. By means of sequential washings the samples were analyzed microbiological and inmunologically, taking Candida albicans ATCC as indicator of the phagocyte activity. It was found that only a mean of 22.02 (± 7.62) of diabetics crevicular leucocytes group have an adequate phagocyte activity compared to 78.64 (± 9.20) of control group. In the same manner a mean of 78.21 (± 7.84) of diabetics crevicular leucocytes group made adherence without ingestion of C.a. compared to only 21.36 (± 9.20) of the control group. The differences between appropriated phagocytosis and ingestion activity of C.a. diabetics’ crevicular leukocytes group and phagocytes of control group were statistical significant, t = 15.5 (p <=0.001), in the same manner the differences between leukocyte adherence without ingestion of C.a. of diabetic group and the control group, were statistical significant, t = 15.4(p <=0.001). El objetivo de la presente investigación fue determinar la existencia de alteraciones en la fagocitosis de los leucocitos creviculares de pacientes diabéticos con Enfermedad Periodontal. Para tal efecto, se seleccionaron 56 individuos con Enfermedad Periodontal: 42 pacientes con diagnóstico de Diabetes Mellitus tipo 2 y 14 sin ella (grupo control), comprendidos entre 35 y 74 años de edad. Para la realización del estudio, se tomó como unidad de análisis los leucocitos provenientes del fluido crevicular de los pacientes en mención. Mediante lavados secuenciales; las muestras fueron analizadas microbiológica e inmunológicamente, teniendo como indicador, de la actividad fagocítica, a la Candida albicans ATCC. Hallándose que sólo el 22,02 (±7,62) de los leucocitos creviculares de diabéticos realiza una adecuada actividad fagocítica frente al 78,64 (±9,20) del grupo control. Asimismo el 78,21 (± 7,84) de los leucocitos creviculares de diabéticos realiza la adherencia leucocitaria sin ingesta del patógeno frente a un 21,36 (± 9,20) del grupo control. Resultando diferencias estadísticamente significativas en la adecuada fagocitosis del grupo de leucocitos creviculares de los diabéticos en relación al grupo control con un valor t= 15,5 (p <=0,001), del mismo modo las diferencias estadísticas fueron significativas en relación de la adherencia leucocitaria sin ingesta del patógeno con un valor t= 15,4 (p<=0,001) referente a los leucocitos creviculares de los pacientes diabéticos frente al grupo control. |
| description |
The goal of this investigation was to find out the alterations in the phagocyte activity of crevicular leucocytes regarding to diabetic patients with periodontal disease. For that reason, 56 patients with periodontal disease were selected: 42 of them with a diagnosis of Diabetes Mellitus - Type 2, and 14 patients without it (control group), from 35 to 74 years old. To performed the study, crevicular fluid of the mentioned patients was analyzed. By means of sequential washings the samples were analyzed microbiological and inmunologically, taking Candida albicans ATCC as indicator of the phagocyte activity. It was found that only a mean of 22.02 (± 7.62) of diabetics crevicular leucocytes group have an adequate phagocyte activity compared to 78.64 (± 9.20) of control group. In the same manner a mean of 78.21 (± 7.84) of diabetics crevicular leucocytes group made adherence without ingestion of C.a. compared to only 21.36 (± 9.20) of the control group. The differences between appropriated phagocytosis and ingestion activity of C.a. diabetics’ crevicular leukocytes group and phagocytes of control group were statistical significant, t = 15.5 (p <=0.001), in the same manner the differences between leukocyte adherence without ingestion of C.a. of diabetic group and the control group, were statistical significant, t = 15.4(p <=0.001). |
| publishDate |
2008 |
| dc.date.none.fl_str_mv |
2008-07-15 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
https://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/3072 10.15381/os.v11i1.3072 |
| url |
https://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/3072 |
| identifier_str_mv |
10.15381/os.v11i1.3072 |
| dc.language.none.fl_str_mv |
spa |
| language |
spa |
| dc.relation.none.fl_str_mv |
https://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/3072/2583 |
| dc.rights.none.fl_str_mv |
Derechos de autor 2008 Jorge R. Colchado Carhuavilca http://creativecommons.org/licenses/by-nc-sa/4.0 info:eu-repo/semantics/openAccess |
| rights_invalid_str_mv |
Derechos de autor 2008 Jorge R. Colchado Carhuavilca http://creativecommons.org/licenses/by-nc-sa/4.0 |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
application/pdf |
| dc.publisher.none.fl_str_mv |
Universidad Nacional Mayor de San Marcos, Facultad de Odontología |
| publisher.none.fl_str_mv |
Universidad Nacional Mayor de San Marcos, Facultad de Odontología |
| dc.source.none.fl_str_mv |
Odontología Sanmarquina; Vol 11 No 1 (2008); 14-18 Odontología Sanmarquina; Vol. 11 Núm. 1 (2008); 14-18 1609-8617 1560-9111 reponame:Revista UNMSM - Odontología Sanmarquina instname:Universidad Nacional Mayor de San Marcos instacron:UNMSM |
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Revista UNMSM - Odontología Sanmarquina |
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Revista UNMSM - Odontología Sanmarquina |
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Universidad Nacional Mayor de San Marcos |
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UNMSM |
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UNMSM |
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mail@mail.com |
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1701385728496238592 |
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13.977305 |
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La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).