Macrolide resistance mechanisms in Enterobacteriaceae: Focus on azithromycin

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From its introduction in 1952 onwards, the clinical use of macrolides has been steadily increasing, both in human and veterinary medicine. Although initially designed to the treatment of Grampositive microorganisms, this antimicrobial family has also been used to treat specific Gram-negative bacteri...

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Detalles Bibliográficos
Autores: Gomes, Cláudia, Martínez Puchol, Sandra, Palma, Noemí, Horna, Gertrudis, Ruiz-Roldán, Lidia, Pons, Maria J, Ruiz, Joaquim
Formato: artículo
Fecha de Publicación:2016
Institución:Universidad Peruana de Ciencias Aplicadas
Repositorio:UPC-Institucional
Lenguaje:inglés
OAI Identifier:oai:repositorioacademico.upc.edu.pe:10757/620710
Enlace del recurso:http://hdl.handle.net/10757/620710
Nivel de acceso:acceso abierto
Materia:23S rRNA
Methylases
Esterases
Phospotransferases;
Ribosomal mutations
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dc.title.es_PE.fl_str_mv Macrolide resistance mechanisms in Enterobacteriaceae: Focus on azithromycin
title Macrolide resistance mechanisms in Enterobacteriaceae: Focus on azithromycin
spellingShingle Macrolide resistance mechanisms in Enterobacteriaceae: Focus on azithromycin
Gomes, Cláudia
23S rRNA
Methylases
Esterases
Phospotransferases;
Ribosomal mutations
title_short Macrolide resistance mechanisms in Enterobacteriaceae: Focus on azithromycin
title_full Macrolide resistance mechanisms in Enterobacteriaceae: Focus on azithromycin
title_fullStr Macrolide resistance mechanisms in Enterobacteriaceae: Focus on azithromycin
title_full_unstemmed Macrolide resistance mechanisms in Enterobacteriaceae: Focus on azithromycin
title_sort Macrolide resistance mechanisms in Enterobacteriaceae: Focus on azithromycin
author Gomes, Cláudia
author_facet Gomes, Cláudia
Martínez Puchol, Sandra
Palma, Noemí
Horna, Gertrudis
Ruiz-Roldán, Lidia
Pons, Maria J
Ruiz, Joaquim
author_role author
author2 Martínez Puchol, Sandra
Palma, Noemí
Horna, Gertrudis
Ruiz-Roldán, Lidia
Pons, Maria J
Ruiz, Joaquim
author2_role author
author
author
author
author
author
dc.contributor.email.es_PE.fl_str_mv joruiz.trabajo@gmail.com
dc.contributor.author.fl_str_mv Gomes, Cláudia
Martínez Puchol, Sandra
Palma, Noemí
Horna, Gertrudis
Ruiz-Roldán, Lidia
Pons, Maria J
Ruiz, Joaquim
dc.subject.es_PE.fl_str_mv 23S rRNA
Methylases
Esterases
Phospotransferases;
Ribosomal mutations
topic 23S rRNA
Methylases
Esterases
Phospotransferases;
Ribosomal mutations
description From its introduction in 1952 onwards, the clinical use of macrolides has been steadily increasing, both in human and veterinary medicine. Although initially designed to the treatment of Grampositive microorganisms, this antimicrobial family has also been used to treat specific Gram-negative bacteria. Some of them, as azithromycin, are considered in the armamentarium against Enterobacteriaceae infections. However, the facility that this bacterial genus has to gain or develop mechanisms of antibiotic resistance may compromise the future usefulness of these antibiotics to fight against Enterobacteriaceae infections. The present review is focused on the mechanisms of macrolide resistance, currently described in Enterobacteriaceae.
publishDate 2016
dc.date.accessioned.none.fl_str_mv 2016-10-28T23:33:20Z
dc.date.available.none.fl_str_mv 2016-10-28T23:33:20Z
dc.date.issued.fl_str_mv 2016-10-27
dc.type.es_PE.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.citation.es_PE.fl_str_mv 1. Gomes C, Martínez-puchol S, Palma N, Horna G, Ruiz-roldán L, Pons MJ, et al. Critical Reviews in Microbiology Macrolide resistance mechanisms in Enterobacteriaceae : Focus on azithromycin Macrolide resistance mechanisms in Enterobacteriaceae : Focus on azithromycin. Crit Rev Microbiol [Internet]. Informa Healthcare USA, Inc; 2016;0(0):000. Available from: http://dx.doi.org/10.3109/1040841X.2015.1136261
dc.identifier.issn.none.fl_str_mv 1040-841X
1549-7828
dc.identifier.doi.none.fl_str_mv 10.3109/1040841X.2015.1136261
dc.identifier.uri.es_PE.fl_str_mv http://hdl.handle.net/10757/620710
dc.identifier.journal.es_PE.fl_str_mv Critical Reviews in Microbiology
identifier_str_mv 1. Gomes C, Martínez-puchol S, Palma N, Horna G, Ruiz-roldán L, Pons MJ, et al. Critical Reviews in Microbiology Macrolide resistance mechanisms in Enterobacteriaceae : Focus on azithromycin Macrolide resistance mechanisms in Enterobacteriaceae : Focus on azithromycin. Crit Rev Microbiol [Internet]. Informa Healthcare USA, Inc; 2016;0(0):000. Available from: http://dx.doi.org/10.3109/1040841X.2015.1136261
1040-841X
1549-7828
10.3109/1040841X.2015.1136261
Critical Reviews in Microbiology
url http://hdl.handle.net/10757/620710
dc.language.iso.es_PE.fl_str_mv eng
language eng
dc.relation.url.es_PE.fl_str_mv https://www.tandfonline.com/doi/full/10.3109/1040841X.2015.1136261
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eu_rights_str_mv openAccess
dc.format.es_PE.fl_str_mv application/pdf
dc.publisher.es_PE.fl_str_mv Taylor & Francis
dc.source.es_PE.fl_str_mv Universidad Peruana de Ciencias Aplicadas (UPC)
Repositorio Académico - UPC
dc.source.none.fl_str_mv reponame:UPC-Institucional
instname:Universidad Peruana de Ciencias Aplicadas
instacron:UPC
instname_str Universidad Peruana de Ciencias Aplicadas
instacron_str UPC
institution UPC
reponame_str UPC-Institucional
collection UPC-Institucional
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spelling Gomes, CláudiaMartínez Puchol, SandraPalma, NoemíHorna, GertrudisRuiz-Roldán, LidiaPons, Maria JRuiz, Joaquimjoruiz.trabajo@gmail.com2016-10-28T23:33:20Z2016-10-28T23:33:20Z2016-10-271. Gomes C, Martínez-puchol S, Palma N, Horna G, Ruiz-roldán L, Pons MJ, et al. Critical Reviews in Microbiology Macrolide resistance mechanisms in Enterobacteriaceae : Focus on azithromycin Macrolide resistance mechanisms in Enterobacteriaceae : Focus on azithromycin. Crit Rev Microbiol [Internet]. Informa Healthcare USA, Inc; 2016;0(0):000. Available from: http://dx.doi.org/10.3109/1040841X.2015.11362611040-841X1549-782810.3109/1040841X.2015.1136261http://hdl.handle.net/10757/620710Critical Reviews in MicrobiologyFrom its introduction in 1952 onwards, the clinical use of macrolides has been steadily increasing, both in human and veterinary medicine. Although initially designed to the treatment of Grampositive microorganisms, this antimicrobial family has also been used to treat specific Gram-negative bacteria. Some of them, as azithromycin, are considered in the armamentarium against Enterobacteriaceae infections. However, the facility that this bacterial genus has to gain or develop mechanisms of antibiotic resistance may compromise the future usefulness of these antibiotics to fight against Enterobacteriaceae infections. The present review is focused on the mechanisms of macrolide resistance, currently described in Enterobacteriaceae.CG has a PhD fellowship of the ISCIII [grant number: FI12/ 00561]. GH has a PhD fellowship from the Schlumberger Foundation – Faculty for The Future Program. LR-R has a PhD fellowship from Sistema Riojano de Innovaci on del Gobierno de La Rioja. MJP has a postdoctoral fellowship from CONCYTEC [grant number: CG05-2013-FONDECYT]. JR has a fellowship from the program I3, of the ISCIII [grant number: CES11/012]. The study was supported by the Generalitat de Catalunya, Departament d’Universitats, Recerca i Societat de la Informaci o [2014 SGR 26] and by the Spanish Network for the Research in Infectious Diseases [REIPI RD12/0015].Revisión por paresapplication/pdfengTaylor & Francishttps://www.tandfonline.com/doi/full/10.3109/1040841X.2015.1136261info:eu-repo/semantics/openAccessUniversidad Peruana de Ciencias Aplicadas (UPC)Repositorio Académico - UPCreponame:UPC-Institucionalinstname:Universidad Peruana de Ciencias Aplicadasinstacron:UPC23S rRNA52de9207-3d59-48b9-b046-f29e9a1dd7f5600Methylasesb2837003-f793-421c-8712-164d008c6088600Esterases52c87e7c-2a2b-4c27-b39d-fe77442e8608600Phospotransferases;c8cb5b95-446d-4e67-8f61-5cdf4391696b600Ribosomal mutationsa77a0541-ae82-4c47-b82b-c912d02fb109600Macrolide resistance mechanisms in Enterobacteriaceae: Focus on azithromycininfo:eu-repo/semantics/article2018-06-18T21:43:47ZFrom its introduction in 1952 onwards, the clinical use of macrolides has been steadily increasing, both in human and veterinary medicine. Although initially designed to the treatment of Grampositive microorganisms, this antimicrobial family has also been used to treat specific Gram-negative bacteria. Some of them, as azithromycin, are considered in the armamentarium against Enterobacteriaceae infections. However, the facility that this bacterial genus has to gain or develop mechanisms of antibiotic resistance may compromise the future usefulness of these antibiotics to fight against Enterobacteriaceae infections. 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Macrolide resistance mechanisms in Enterobacteriaceae: Focus on azithromycin
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